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Metabolic Adaptations of Uropathogenic E. coli in the Urinary Tract [PDF]
Escherichia coli ordinarily resides in the lower gastrointestinal tract in humans, but some strains, known as Uropathogenic E. coli (UPEC), are also adapted to the relatively harsh environment of the urinary tract. Infections of the urine, bladder and kidneys by UPEC may lead to potentially fatal bloodstream infections.
Riti Mann +2 more
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Pathogenicity islands of uropathogenic E. coli and the evolution of virulence
International Journal of Antimicrobial Agents, 2002Uropathogenic Escherichia coli (UPEC) are the most important group of microorganisms responsible for urinary tract infection. UPEC differ from non-pathogenic E. coli and from other E. coli pathotypes by the production of specific virulence factors, which enable the bacteria to adhere to uroepithelial cells and to establish urinary tract infections ...
T A, Oelschlaeger +2 more
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Biofilm formation by ESBL-producing uropathogenic E. coli
International Journal of Pharmaceutical Sciences and Nanotechnology(IJPSN), 2022Introduction: E. coli is considered to be the leading cause of urinary tract infections. (UTIs) and is responsible for both community acquired and hospital acquired UTIs. The ability of this bacterium to form biofilm on various devices like catheters plays an important role in progression of the disease.
MANJULA MEHTA +4 more
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Virulence Factors of Uropathogenic E. coli and Their Interaction with the Host
2014Urinary tract infections (UTIs) belong to the most common infectious diseases worldwide. The most frequently isolated pathogen from uncomplicated UTIs is Escherichia coli. To establish infection in the urinary tract, E. coli has to overcome several defence strategies of the host, including the urine flow, exfoliation of urothelial cells, endogenous ...
Petra, Lüthje, Annelie, Brauner
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Extra-Intestinal Escherichia coli (Uropathogenic E. coli and Avian Pathogenic E. coli)
2016Extra-intestinal pathogenic E. coli (ExPEC) is the most common Gram-negative bacterial pathogen, and it is associated to many animal diseases. Within the ExPEC classification are the uropathogenic Escherichia coli strains that are able to cause pyelonephritis, prostatitis, and catheter-associated urinary tract infections (UTIs) as well as community ...
Janaína L. Leite +3 more
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Role of ATG16L1 in Uropathogenic E. Coli Pathogenesis
2016Urinary tract infections (UTIs) are among the most common infectious diseases and are primarily caused by uropathogenic E. coli (UPEC). Given the greater incidence of antibiotic resistance among UPEC isolates, it is vital to determine factors and pathways important for an effective host response to UPEC in order to improve therapeutic options for ...
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Target analysis of α-alkylidene-γ-butyrolactones in uropathogenic E. coli
Molecular BioSystems, 2012Abstract α-Alkylidene-γ-butyrolactones are quite common in nature and exhibit a broad spectrum of biological activities. We therefore synthesized a small library of xanthatine inspired α-alkylidene-γ-butyrolactones to screen non-pathogenic and uropathogenic E. coli strains by activity based protein profiling (ABPP).
Martin H. Kunzmann, Stephan A. Sieber
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Horizontal transfer of class 1 integrons from uropathogenic Escherichia coli to E. coli K12
Microbial Pathogenesis, 2018Class 1 integrons are genetic elements that carry a variable set of antibiotic resistance genes, being frequently found in clinical Gram-negative isolates. It is generally assumed that they easily spread horizontally among bacteria, thus contributing to the appearance of multidrug resistant clones.
María Eloísa, Poey, Magela, Laviña
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[Methods of detection of P-fimbria in uropathogenic E. coli].
Ceskoslovenska epidemiologie, mikrobiologie, imunologie, 1993We characterized the surface properties of E. coli strains isolated from urine of children with urinary tract infections. The PF test and haemagglutination reaction were used for detection of P-fimbriae. P-fimbriae were detected in 30-54% of the pyelonephritic strains. All these strains expressed P-fimbriae in vitro.
G, Bartková, I, Ciznár
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