Results 21 to 30 of about 24,277 (210)

Estrogen-stimulated uropathogenic E. coli mediate enhanced neutrophil responses. [PDF]

Sci Rep
AbstractUrinary tract infection (UTI) is one of the most common bacterial infections worldwide and the most common cause is uropathogenic Escherichia coli (UPEC). Current research is mostly focused on how UPEC affects host factors, whereas the effect of host factors on UPEC is less studied.
Pettersson C, Wu R, Demirel I.
europepmc   +5 more sources

Insightful Improvement in the Design of Potent Uropathogenic E. coli FimH Antagonists. [PDF]

Pharmaceutics, 2023
Selective antiadhesion antagonists of Uropathogenic Escherichia coli (UPEC) type-1 Fimbrial adhesin (FimH) are attractive alternatives for antibiotic therapies and prophylaxes against acute or recurrent urinary tract infections (UTIs) caused by UPECs.
Mousavifar L, Sarshar M, Bridot C, Scribano D, Ambrosi C, Palamara AT, Vergoten G, Roubinet B, Landemarre L, Bouckaert J, Roy R.   +10 more
europepmc   +5 more sources

Subversion of host innate immunity by uropathogenic Escherichia coli [PDF]

, 2016
Uropathogenic Escherichia coli (UPEC) cause the majority of community-onset urinary tract infections (UTI) and represent a major etiologic agent of healthcare-associated UTI.
Cavalieri, Godaly, Hagberg, Hedges, Schappert, Shahin   +5 more
core   +3 more sources

C5aR1 promotes acute pyelonephritis induced by uropathogenic E. coli [PDF]

JCI Insight, 2017
C5a receptor 1 (C5aR1) is a G protein-coupled receptor for C5a and also an N-linked glycosylated protein. In addition to myeloid cells, C5aR1 is expressed on epithelial cells. In this study, we examined the role of C5aR1 in bacterial adhesion/colonization of renal tubular epithelium and addressed the underlying mechanisms of this role.
Li K, Wu KY, Wu W, Wang N, Zhang T, Choudhry N, Song Y, Farrar CA, Ma L, Wei LL, Duan ZY, Dong X, Liu EQ, Li ZF, Sacks SH, Zhou W   +15 more
openaire   +3 more sources

In Vitro Coliform Resistance to Bioactive Compounds in Urinary Infection, Assessed in a Lab Catheterization Model

Applied Sciences, 2021
Bioactive compounds and phenolic compounds are viable alternatives to antibiotics in recurrent urinary tract infections. This study aimed to use a natural functional product, based on the bioactive compounds’ composition, to inhibit the uropathogenic ...
Emanuel Vamanu, Laura Dorina Dinu, Cristina Mihaela Luntraru, Alexandru Suciu   +3 more
doaj   +1 more source

The structure of the PapD-PapGII pilin complex reveals an open and flexible P5 pocket [PDF]

, 2012
P pili are hairlike polymeric structures that mediate binding of uropathogenic Escherichia coli to the surface of the kidney via the PapG adhesin at their tips.
Baga M, Bann JG, Barnhart MM, Dodson KW, Dodson KW, Doublie S, Gong M, Griebling TL, Henderson NS, Hess B, Holmgren A, Hooton TM, Hultgren SJ, Hung DL, Hung DL, Hung DL, Jacob-Dubuisson F, Jones CH, Justice SS, Kabsch W, Knight SD, Kuehn MJ, Kuehn MJ, Leslie A, Martinez JJ, Munera D, Nishiyama M, Painter J, Pellecchia M, Phan G, Remaut H, Remaut H, Roberts JA, Roberts JA, Rose RJ, Sauer FG, Sauer FG, Sauer FG, Saulino ET, Saulino ET, Sheldrick GM, Slonim LN, Striker R, Stromberg N, Verger D, Verger D, Volkan E, Wright KJ, Zavialov AV   +48 more
core   +2 more sources

Differential Effects of Uropathogenic and Non-Uropathogenic <i>E. coli</i> on the Mouse Urobiome and Urine NGAL Levels. [PDF]

Res Rep Urol
Olivia Kathryn Lamanna,1,2 Rong Hu,3 Mark Khemmani,4 Alan J Wolfe,4 Suzanne L Groah,5 Catherine S Forster6,7 1Biomedical Research Institute, Rockville, MD, USA; 2Uniformed Services University, Bethesda, MD, USA; 3Department of Oncology, Georgetown University, Washington, DC, USA; 4Department of Microbiology and Immunology, Loyola University Chicago ...
Lamanna OK, Hu R, Khemmani M, Wolfe AJ, Groah SL, Forster CS.   +5 more
europepmc   +3 more sources

Biofilm formation, antimicrobial susceptibility and virulence genes of Uropathogenic Escherichia coli isolated from clinical isolates in Uganda

BMC Infectious Diseases, 2020
Introduction Uropathogenic E. coli is the leading cause of Urinary tract infections (UTIs), contributing to 80–90% of all community-acquired and 30–50% of all hospital-acquired UTIs. Biofilm forming Uropathogenic E.
Paul Katongole, Fatuma Nalubega, Najjuka Christine Florence, Benon Asiimwe, Irene Andia   +4 more
doaj   +1 more source

Efficacy of Fosfomycin against Extended Spectrum Beta-Lactamase-Producing Escherichia coli Isolated from Patient Urinary Cultures in the General Reference Hospital of Niamey, Niger

Uro, 2023
Urinary tract infection (UTI) is a common patient infection and a major public health problem today. The rapid spread of antibiotic resistance genes in Enterobacterales, particularly in Extended-spectrum beta-lactamases producing Escherichia coli (ESBL-E.
Alassane Halawen Mohamed, René Dembélé, Alio Mahamadou Fody, Alix Bénédicte Kagambèga, Hiliassa Coulibaly, Frédéric François Bado, Chaibou Salaou, Laouali Boubou, Alkassoum Ibrahim, Eric Adehossi Omar, Nicolas Barro   +10 more
doaj   +1 more source

Comparative proteomics of uropathogenic Escherichia coli during growth in human urine identify UCA-like (UCL) fimbriae as an adherence factor involved in biofilm formation and binding to uroepithelial cells [PDF]

, 2015
Uropathogenic Escherichia coli (UPEC) are the primary cause of urinary tract infection (UTI) in humans. For the successful colonisation of the human urinary tract, UPEC employ a diverse collection of secreted or surface-exposed virulence factors ...
Allsopp, LP, Moriel, DG, Schembri, MA, Totsika, M, Webb, RI, Wurpel, DJ   +5 more
core   +1 more source