IJU Case Reports, Volume 9, Issue 2, March 2026.ABSTRACT Introduction Upper tract urothelial carcinoma with neuroendocrine differentiation (UC‐NE) is extremely rare and generally associated with aggressive behavior and poor prognosis. Optimal treatment strategies remain unclear, particularly regarding the role of nectin‐4–targeted therapy. Case Presentation A 61‐year‐old man was diagnosed with UC‐NE
Kosei Taniguchi +9 more
wiley +1 more source
Treatment Optimization and Management of AEs with Enfortumab Vedotin + Pembrolizumab for Untreated Locally Advanced/Metastatic Urothelial Cancer: A Podcast. [PDF]
Oncol TherPowles T, Lapuente M, Garmezy B.
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IJU Case Reports, Volume 9, Issue 2, March 2026.ABSTRACT Introduction Peritoneal carcinomatosis in patients with advanced bladder cancer is a rare but lethal event following robot‐assisted radical cystectomy (RARC). We report a case of an unusual clinical course in which peritoneal dissemination of colon cancer was unexpectedly detected seven months after RARC.
Kana Ito +8 more
wiley +1 more source
The Role of Antibody-Drug Conjugates in Urothelial Cancer: A Review of Recent Advances in the Treatment of Locally Advanced and Metastatic Urothelial Cancer. [PDF]
Clin Med Insights OncolVlachou E +2 more
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IJU Case Reports, Volume 9, Issue 2, March 2026.ABSTRACT Introduction Bladder cancer (BC) is rarely associated with common bile duct (CBD) obstruction. We report a case of BC with peritoneal invasion and rectal involvement complicated by bilateral ureteral and biliary obstruction. Case Presentation A 77‐year‐old man presented with abdominal pain.
Kazuto Imai +6 more
wiley +1 more source
Impact of treatment patterns and sequencing on clinical and economic outcomes in patients with metastatic urothelial cancer: IMPACT UC II study. [PDF]
OncologistBilen MA +8 more
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IJU Case Reports, Volume 9, Issue 2, March 2026.ABSTRACT Introduction Avelumab maintenance after response to platinum chemotherapy improves outcomes in metastatic urothelial carcinoma. Progression during maintenance presents a therapeutic dilemma. Case Presentation A 72‐year‐old man underwent radical cystectomy and left nephroureterectomy for high‐grade urothelial carcinoma.
Fumihiro Ito +4 more
wiley +1 more source
Balancing effectiveness, toxicity, and individualization: enfortumab vedotin in advanced urothelial cancer. [PDF]
Transl Androl UrolWang N, Tully KH.
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Microbiome‐urothelium crosstalk in bladder cancer: From dysbiosis to clinical translation
iMetaOmics, Volume 3, Issue 1, March 2026.This review elucidates the critical crosstalk between the urobiome and bladder cancer (BCa), mapping the landscape from ecological dysbiosis to clinical translation. We synthesize emerging evidence on microbial signatures that distinguish BCa patients, exploring key carcinogenic mechanisms including chronic inflammation, genotoxicity, and the gut ...
Haoxiang Xu +14 more
wiley +1 more source
Intravesical instillation of chemotherapy before surgery for upper tract urothelial cancer. [PDF]
Bladder CancerMessing EM, Malshy K.
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