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Proliferative pattern of urothelial bladder cancer and urothelial atypias
Journal of Cancer Research and Clinical Oncology, 1985For early diagnosis of urinary bladder tumors, autoradiographic, cytological, and impulse cytophotometric examinations were performed on fresh bladder tissue with carcinomas of different grades of malignancy and various depths of infiltration, and also on tissues with concomitant urothelial atypias.
B, Helpap, H W, Schwabe, H D, Adolphs
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Urothelial Differentiation and Bladder Cancer
1999Cancer is the endpoint of a multi-step process of carcinogenesis.1–5 This process involves multiple genetic and epigenetic alterations and cellular selections.2–4,6 These changes result in cell populations with unregulated growth and ultimately, the ability to invade and metastasize.
M, Liebert +6 more
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Gemcitabine/Carboplatin in Advanced Urothelial Cancer
Seminars in Oncology, 2001Transitional cell carcinoma of the urothelium is a highly chemosensitive tumor. Combination chemotherapy can provide both palliation and a modest survival advantage in patients with advanced disease. As shown in a recent phase III trial, the new gold standard should be considered gemcitabine/cisplatin, although toxicity remains important.
J, Carles, M, Nogué
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Urothelial Cancer Stem Cell Heterogeneity
2019Urothelial carcinoma is a tumor type featuring pronounced intertumoral heterogeneity and a high mutational and epigenetic load. The two major histopathological urothelial carcinoma types - the non-muscle-invasive and muscle-invasive urothelial carcinoma - markedly differ in terms of their respective typical mutational profiles and also by their ...
Michaela, Kripnerova +7 more
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Emerging treatments in advanced urothelial cancer
Current Opinion in Oncology, 2020Purpose of review Urothelial carcinoma is one of the 10 most common forms of cancer in the world with more than half a million cases diagnosed yearly. The past few years have witnessed a revolution in understanding the biology of urothelial carcinoma and the development of promising therapies.
Omar, Alhalabi +4 more
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2020
Urothelial Carcinoma is defined as the abnormal division of cells within the layers of tissue or urothelium of the renal pelvis, bladder, ureters, and the urethra. Cancer of the bladder, ureters, and urethra most commonly are missed diagnosed as urinary tract infections or nephrolithiasis.
Anne Lizardi-Calvaresi +2 more
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Urothelial Carcinoma is defined as the abnormal division of cells within the layers of tissue or urothelium of the renal pelvis, bladder, ureters, and the urethra. Cancer of the bladder, ureters, and urethra most commonly are missed diagnosed as urinary tract infections or nephrolithiasis.
Anne Lizardi-Calvaresi +2 more
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Advanced bladder and urothelial cancers
European Journal of Cancer, 2000After more than 40 years of use, cytotoxic chemotherapy has an evolving role in the management of advanced bladder cancer. Standard single-agent regimens, such as methotrexate, doxorubicin, vinblastine and cisplatin, have produced objective response rates of 15-25%, and combination chemotherapy causes objective regression in 50-75% of cases.
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Non-urothelial Bladder Cancers
2015Non-urothelial bladder cancers include squamous cell carcinoma, adenocarcinoma and the non-epithelial bladder tumours (NEBT).
Said Abdallah Al-Mamari +1 more
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Surgery (Oxford), 2016
Abstract Upper tract transitional cell carcinoma is a lethal disease with half the patients dead within 5 years of diagnosis. Unlike urothelial tumours arising in the bladder, the disease is more likely to be invasive at the time of diagnosis and in part reflects the poorer prognosis.
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Abstract Upper tract transitional cell carcinoma is a lethal disease with half the patients dead within 5 years of diagnosis. Unlike urothelial tumours arising in the bladder, the disease is more likely to be invasive at the time of diagnosis and in part reflects the poorer prognosis.
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