Results 81 to 90 of about 3,069,601 (247)

Role of galectin-1 in urinary bladder urothelial carcinoma cell invasion through the JNK pathway

open access: yes, 2016
[[abstract]]Human galectin-1 is a member of the galectin family, proteins with conserved carbohydrate-recognition domains that bind galactoside. Galectin-1 is highly expressed in various tumors and participates in various oncogenic processes.
Shen, KH;Li, CF;Chien, LH;Huang, CH;Su, CC;Liao, AC;Wu, TF
core   +1 more source

Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art

open access: yesAdvanced Intelligent Discovery, EarlyView.
Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser   +6 more
wiley   +1 more source

Androgen receptor in bladder cancer: A promising therapeutic target

open access: yesAsian Journal of Urology, 2020
There has been a significant progress in the treatment of metastatic urothelial carcinoma in the last few years with the advent of immunotherapy after a long gap of no drug approvals for over 4 decades.
Abhishek Tripathi, Shilpa Gupta
doaj   +1 more source

Cancer Trends: Cervical cancer

open access: yes, 2017
In the period 2013-2015, invasive cancer of the cervix uteri (ICD10: C53) accounted for just over 1% of all invasive cancers (excluding non-melanoma skin cancer) in Ireland, with an average of 262 cases diagnosed per year.
National Cancer Registry Ireland (NCRI)
core  

Cyclooxygenase-2 Expression in Bladder Cancer and Patient Prognosis: Results from a Large Clinical Cohort and Meta-Analysis [PDF]

open access: yes, 2012
27/02/14 meb.
Manuel M. Morente (135761)   +58 more
core   +1 more source

Cancer Trends: Cancer of the liver and biliary tract

open access: yes, 2010
Liver cancer consists of two main types—hepatocellular carcinoma (HCC) which accounts for about 60% of cases, and intrahepatic bile duct cholangiocarcinoma (ICC), which accounts for about 20%. The liver is one of the less common cancer sites, about 0.
National Cancer Registry Ireland (NCRI)
core  

Status of oncology drugs with a conditional approval: A cross‐sectional comparison of the Food and Drug Administration and Health Canada

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study looks at the status of the same drugs conditionally approved by the Food and Drug Administration and Health Canada for the same oncology indication. Methods Lists of oncology drugs with a conditional approval from the Food and Drug Administration and Health Canada were generated and drug pairs with the same indication were matched ...
Joel Lexchin
wiley   +1 more source

Locally advanced invasive urothelial cancer of the lower third of the ureter in a high-risk patient (clinical observation)

open access: yesИзвестия высших учебных заведений. Поволжский регион: Медицинские науки
Background. Urothelial carcinoma of the upper urinary tract is considered a rare pathology in the practice of a urologist or oncologist. This tumor is quite aggressive in nature: for example, 60% of urothelial cancer cases at the time of diagnosis are ...
A.Z. Almyashev   +5 more
doaj   +1 more source

Cancer Trends: Breast cancer 1994-2016

open access: yes, 2019
There were 62,052 cases of newly diagnosed invasive or in situ breast tumours registered in Ireland by the National Cancer Registry for the period 1994–2016, of which 56,366 were invasive (ICD10: C50) and 5,686 were carcinoma in situ (ICD10: D05 ...
National Cancer Registry Ireland (NCRI)
core  

Regulatory harmonization: Evolution, globalization and future directions

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm   +2 more
wiley   +1 more source

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