Results 141 to 150 of about 14,292 (181)
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Journal of Urology, 1992
We have been investigating the nature of the mucosal lining of human urinary bladder. Surface material was obtained from bladders at autopsy and used for biochemical analysis. Western immunoblotting and tissue immunochemistry identified a molecule of Mr 28,000 (28K) which is present within surface cells of the urothelium (umbrella cells).
J Z, Montgomerie +3 more
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We have been investigating the nature of the mucosal lining of human urinary bladder. Surface material was obtained from bladders at autopsy and used for biochemical analysis. Western immunoblotting and tissue immunochemistry identified a molecule of Mr 28,000 (28K) which is present within surface cells of the urothelium (umbrella cells).
J Z, Montgomerie +3 more
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Mechanotransduction in the urothelium
2023The urothelium, which covers the inner surface of the bladder, is continuously exposed to a complex physical environment where it is stimulated by and responds to a wide range of mechanical cues. Mechanically activated ion channels allow the urothelium to convert mechanical stimuli into biochemical events that influence its surface area and the ...
Xu Li +5 more
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Development, regeneration and tumorigenesis of the urothelium
Development, 2022ABSTRACT The urothelium of the bladder functions as a waterproof barrier between tissue and outflowing urine. Largely quiescent during homeostasis, this unique epithelium rapidly regenerates in response to bacterial or chemical injury. The specification of the proper cell types during development and injury repair is crucial for tissue ...
Gregory B. Wiessner +3 more
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Urothelium-specific antibody and lectin surface mapping of bladder urothelium
The Histochemical Journal, 1982Coupled ligand-colloidal gold complexes were found to provide a convenient approach for the localization of scanning electron microscopy of cell surface membrane antigens and lectin-binding sites on bladder urothelium and for the immunocytochemical identification of urothelial cell populations at different stages of differentiation. The ligands used to
G M, Hodges +2 more
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Vesical Urothelium and New Concepts
Urologia Journal, 2012Vesical urothelium was long considered to simply be a protection barrier, which passively separates the urinary content from the underlying smooth muscle and the blood stream. Recent observations, though, have pointed out that vesical urothelium cells have clear active and sensory functions, in response to various physical and chemical stimuli.
GIANNANTONI, Antonella +3 more
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The Urothelium: A Battleground for Oncogenesis
Journal of Urology, 1978A discussion of the term urothelium and reasons for its general adoption are presented. The unique asymmetric unit membrane of the superficial cells is described and its function as a significant barrier against water, some electrolytes and so forth is reviewed. The urothelium bears the brunt of the attack by pollutants and various oncogens.
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Colistin interactions with the mammalian urothelium
American Journal of Physiology-Cell Physiology, 2004Here we describe the effect of colistin on the barrier function of the mammalian urinary bladder epithelium. Addition of colistin to the mucosal solution of the rabbit urinary bladder epithelium (urothelium) resulted in an increase in the transepithelial conductance.
Jamie R, Lewis, Simon A, Lewis
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Tissueâengineered Artificial Urothelium
World Journal of Surgery, 2000AbstractBladder wall replacement is one of the most challenging problems of urologic surgery. Various materials have been tried in experimental models, but most were not free of complications, such as leakage, infection, and stone formation. In addition, much time was needed for tissue regeneration after grafting.
K, Kawai, K, Hattori, H, Akaza
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Imaging the urothelium with OCT
Therapeutics and Diagnostics in Urology 2020, 2020The bladder urothelium is usually considered as an impermeable barrier to urine, but recent reports pointed that it was not only a passive impermeable membrane but also has some sensory and signaling functions. While aquaporin expression has been found in the urothelium, which implicits water transportation through the urothelium, it has never been ...
Lan Dao, Xu Zhou, Hui Wang
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Effects of Formalin on Bladder Urothelium
Journal of Urology, 1975Formalin instillation into canine bladders was followed by serial radiographic and histologic evaluation. A generalized slough of epithelial tissue was seen with the deposition of an amorphous substance. Telangiectasia resulted in moderate bleeding.
J R, Whittaker, S Z, Freed
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