Results 181 to 190 of about 23,614 (207)

Treatment of Bladder Urothelium Injury

Urologia Journal, 2015
The management of patients with cystitis-related symptoms due to urinary tract infection, bladder pain syndrome (BPS) or radio/chemo-induced cystitis remains challenging. A component in the pathophysiology of these symptoms relates to the fact that the urothelium is a highly metabolically active structure and that alterations in this structure can ...
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Colistin interactions with the mammalian urothelium

American Journal of Physiology-Cell Physiology, 2004
Here we describe the effect of colistin on the barrier function of the mammalian urinary bladder epithelium. Addition of colistin to the mucosal solution of the rabbit urinary bladder epithelium (urothelium) resulted in an increase in the transepithelial conductance.
Jamie R, Lewis, Simon A, Lewis
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Imaging the urothelium with OCT

Therapeutics and Diagnostics in Urology 2020, 2020
The bladder urothelium is usually considered as an impermeable barrier to urine, but recent reports pointed that it was not only a passive impermeable membrane but also has some sensory and signaling functions. While aquaporin expression has been found in the urothelium, which implicits water transportation through the urothelium, it has never been ...
Lan Dao, Xu Zhou, Hui Wang
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Cells in Urothelium Tissue Engineering

2021
Urothelium is a highly specialized epithelium covering the entire urinary excretory system. Tissue engineering of this urinary tract may allow to consider its reconstruction to perform in vitro studies or in vivo replacement. Therefore, the question of specific reconstruction of the urothelium arises in order to guarantee the neotissue’s ability to act
Berte, N., Mazeaud, C., Eschwege, P., Gillet, P., Pinzano, A., Lemelle, J.L., Grossin, L.   +6 more
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The Urothelium: A Battleground for Oncogenesis

Journal of Urology, 1978
A discussion of the term urothelium and reasons for its general adoption are presented. The unique asymmetric unit membrane of the superficial cells is described and its function as a significant barrier against water, some electrolytes and so forth is reviewed. The urothelium bears the brunt of the attack by pollutants and various oncogens.
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Urothelium‐dependent and urothelium‐independent detrusor contractility mediated by nitric oxide synthase and cyclooxygenase inhibition

Neurourology and Urodynamics, 2011
AbstractAimsThe urothelium has been implicated in regulating detrusor smooth muscle contractility but the identity of the putative urothelium‐derived inhibitory factor remains unconfirmed. There was inconclusive evidence on the role of nitric oxide synthase (NOS) and cyclooxygenase (COX) in mediating detrusor contractions.
Aneira Gracia Hidayat, Santoso, Wan Ning, Lo, Willmann, Liang   +2 more
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Susceptibility of urothelium to neoplastic cellular implantation

Urology, 1975
This study sought to determine whether or not transitional carcinoma cells can adhere and progressively grow on normal or inflamed bladder urothelium. Inflammation was produced by intravesical N-methyl-N-nitrosourea. Tumor cell implantation occurred in only 13 per cent of mice with normal bladder, whereas in the presence of an altered urothelial ...
T E, Weldon, M S, Soloway
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Ultrastructure of the Urothelium

1993
The composition of the urine in mammals is determined by the interaction of filtration pressures and concentration gradients and by a hormonally controlled enzyme transport system in the kidneys. The urine collected in the bladder is usually hypertonic and differs substantially from blood plasma in its organic and inorganic constituents.
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Permeability of Differentiated Human Urothelium In Vitro

2011
The urothelium plays a critical role in the bladder as a permeability barrier to urine. Whereas it was once considered a simple physical barrier, it is increasingly evident that urothelium has a regulatory role in maintaining the barrier both through self-repair and by mediating the transport of ions and small molecules across the transcellular and ...
Peter, Rubenwolf, Jennifer, Southgate
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Role of the urothelium in bladder function

Scandinavian Journal of Urology and Nephrology, 2004
Historically, the urinary bladder urothelium has been viewed as a passive barrier; however, recent evidence has demonstrated that the urothelium is a responsive structure, which exhibits both "sensor" (i.e. ability to respond to thermal, mechanical and chemical stimuli) and "transducer" (i.e. ability to release chemicals) functions.
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