Results 171 to 180 of about 23,871 (225)

Paediatric bladder melanosis: a rare case report. [PDF]

Urol Case Rep
Woodhouse S, Cho A, Tyraskis A, Sanchez S, Sekar T.   +4 more
europepmc   +1 more source

Expression of Nectin-4 and Trop-2 in upper tract urothelial carcinoma: implications for biomarker-driven antibody-drug conjugate therapy. [PDF]

J Pathol Clin Res
Shi P, Wu Q, Zhang Y, Chen T, Warrick JI, DeGraff DJ, Raman JD, Chen G.   +7 more
europepmc   +1 more source

Field-effect-informed urine liquid biopsy for bladder cancer. [PDF]

Cell
Shi WY, Liu KJ, Esfahani MS, Mach KE, Phillips NA, Almanza D, Bajpai RK, Schroers-Martin JG, Trabanino L, Lee TJ, La V, Rodriguez G, Holton G, Chen SB, Mullane P, Wu DJ, Nesselbush MC, Sugio T, Cheng JC, Jabara I, Hamilton EG, Alig SK, Liu CL, Peterson DJ, Prado K, Shkolyar E, Thong A, Shah JB, Gill H, Kunder CA, Chan E, Khaki AR, Skinner EC, Alizadeh AA, Liao JC, Diehn M.   +35 more
europepmc   +1 more source

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Role of the urothelium in bladder function

Scandinavian Journal of Urology and Nephrology, 2004
Historically, the urinary bladder urothelium has been viewed as a passive barrier; however, recent evidence has demonstrated that the urothelium is a responsive structure, which exhibits both "sensor" (i.e. ability to respond to thermal, mechanical and chemical stimuli) and "transducer" (i.e. ability to release chemicals) functions.
Lori A Birder
exaly   +3 more sources

Tissue engineering in urothelium regeneration

Advanced Drug Delivery Reviews, 2015
The development of therapeutic treatments to regenerate urothelium, manufacture tissue equivalents or neourethras for in-vivo application is a significant challenge in the field of tissue engineering. Many studies have focused on urethral defects that, in most cases, inadequately address current therapies.
Martin Vaegler, Bastian Amend, Karl-Dietrich Sievert   +2 more
exaly   +4 more sources

Formation and regeneration of the urothelium

Current Opinion in Organ Transplantation, 2014
This review addresses significant changes in our understanding of urothelial development and regeneration. Understanding urothelial differentiation will be important in the push to find new methods of bladder reconstruction and augmentation, as well as identification of bladder cancer stem cells.This review will cover recent findings including the ...
Tammer, Yamany, Jason, Van Batavia, Cathy, Mendelsohn   +2 more
openaire   +2 more sources

28K Antigen in the Urothelium

Journal of Urology, 1992
We have been investigating the nature of the mucosal lining of human urinary bladder. Surface material was obtained from bladders at autopsy and used for biochemical analysis. Western immunoblotting and tissue immunochemistry identified a molecule of Mr 28,000 (28K) which is present within surface cells of the urothelium (umbrella cells).
J Z, Montgomerie, A J, Keyser, H J, Holshuh, D G, Schick   +3 more
openaire   +2 more sources

Urothelium-specific antibody and lectin surface mapping of bladder urothelium

The Histochemical Journal, 1982
Coupled ligand-colloidal gold complexes were found to provide a convenient approach for the localization of scanning electron microscopy of cell surface membrane antigens and lectin-binding sites on bladder urothelium and for the immunocytochemical identification of urothelial cell populations at different stages of differentiation. The ligands used to
G M, Hodges, M A, Smolira, L K, Trejdosiewicz   +2 more
openaire   +2 more sources

Mechanotransduction in the urothelium

2023
The urothelium, which covers the inner surface of the bladder, is continuously exposed to a complex physical environment where it is stimulated by and responds to a wide range of mechanical cues. Mechanically activated ion channels allow the urothelium to convert mechanical stimuli into biochemical events that influence its surface area and the ...
Xu Li, Junwei Hu, Yuan Wu, Ping Yin, Lumin Liu, Yuelai Chen   +5 more
openaire   +1 more source

Development, regeneration and tumorigenesis of the urothelium

Development, 2022
ABSTRACT The urothelium of the bladder functions as a waterproof barrier between tissue and outflowing urine. Largely quiescent during homeostasis, this unique epithelium rapidly regenerates in response to bacterial or chemical injury. The specification of the proper cell types during development and injury repair is crucial for tissue ...
Gregory B. Wiessner, Sakina A. Plumber, Tina Xiang, Cathy L. Mendelsohn   +3 more
openaire   +2 more sources