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Vesical Urothelium and New Concepts

Urologia Journal, 2012
Vesical urothelium was long considered to simply be a protection barrier, which passively separates the urinary content from the underlying smooth muscle and the blood stream. Recent observations, though, have pointed out that vesical urothelium cells have clear active and sensory functions, in response to various physical and chemical stimuli.
GIANNANTONI, Antonella   +3 more
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The Urothelium: A Battleground for Oncogenesis

Journal of Urology, 1978
A discussion of the term urothelium and reasons for its general adoption are presented. The unique asymmetric unit membrane of the superficial cells is described and its function as a significant barrier against water, some electrolytes and so forth is reviewed. The urothelium bears the brunt of the attack by pollutants and various oncogens.
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Colistin interactions with the mammalian urothelium

American Journal of Physiology-Cell Physiology, 2004
Here we describe the effect of colistin on the barrier function of the mammalian urinary bladder epithelium. Addition of colistin to the mucosal solution of the rabbit urinary bladder epithelium (urothelium) resulted in an increase in the transepithelial conductance.
Jamie R, Lewis, Simon A, Lewis
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Tissue‐engineered Artificial Urothelium

World Journal of Surgery, 2000
AbstractBladder wall replacement is one of the most challenging problems of urologic surgery. Various materials have been tried in experimental models, but most were not free of complications, such as leakage, infection, and stone formation. In addition, much time was needed for tissue regeneration after grafting.
K, Kawai, K, Hattori, H, Akaza
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Imaging the urothelium with OCT

Therapeutics and Diagnostics in Urology 2020, 2020
The bladder urothelium is usually considered as an impermeable barrier to urine, but recent reports pointed that it was not only a passive impermeable membrane but also has some sensory and signaling functions. While aquaporin expression has been found in the urothelium, which implicits water transportation through the urothelium, it has never been ...
Lan Dao, Xu Zhou, Hui Wang
openaire   +1 more source

Effects of Formalin on Bladder Urothelium

Journal of Urology, 1975
Formalin instillation into canine bladders was followed by serial radiographic and histologic evaluation. A generalized slough of epithelial tissue was seen with the deposition of an amorphous substance. Telangiectasia resulted in moderate bleeding.
J R, Whittaker, S Z, Freed
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Ultrastructure of the Urothelium

1993
The composition of the urine in mammals is determined by the interaction of filtration pressures and concentration gradients and by a hormonally controlled enzyme transport system in the kidneys. The urine collected in the bladder is usually hypertonic and differs substantially from blood plasma in its organic and inorganic constituents.
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Effect of Intravesical Formalin on the Urothelium

British Journal of Urology, 1979
Summary— In an experimental study, the urinary bladder of the rabbit was subjected to 10% formaldehyde instillation for periods ranging from 15 to 90 min. Varying degrees of cystitis, ranging from focal superficial to transmural necrotising cystitis, epithelial sloughs and intra‐epithelial calcification may be ...
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Mutational selection in normal urothelium

Science, 2020
Mutations in normal tissue point to causes of DNA damage and set the stage for ...
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Treatment of Bladder Urothelium Injury

Urologia Journal, 2015
The management of patients with cystitis-related symptoms due to urinary tract infection, bladder pain syndrome (BPS) or radio/chemo-induced cystitis remains challenging. A component in the pathophysiology of these symptoms relates to the fact that the urothelium is a highly metabolically active structure and that alterations in this structure can ...
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