Results 121 to 130 of about 28,025 (230)
ABSTRACT Aim Bile acids accumulation in hepatocytes causes liver damage and contributes to the development of hepatocellular carcinoma. However, the association between serum bile acid levels and postoperative intrahepatic recurrence in hepatocellular carcinoma remains unclear.
Tomoaki Bekki +9 more
wiley +1 more source
GLP‐1 agonists and the gut microbiome: A bidirectional relationship
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath +2 more
wiley +1 more source
Застосування урсодезоксихолевої кислоти при лікуванні функціональних розладів біліарної системи [PDF]
В огляді літератури подані сучасні відомості щодо застосування урсодезоксихолевої кислоти при лікуванні функціональних розладів біліарної системи. Для написання статті здійснювався пошук інформації з використанням баз даних Scopus, Web of Science ...
Бабич, В.Л.
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ABSTRACT Acute intermittent porphyria (AIP) is a rare heme biosynthesis disorder in which the accumulation of neurotoxic porphyrin precursors precipitates neurovisceral attacks. Intercurrent infections, including coronavirus disease 2019 (COVID‐19), may trigger or exacerbate AIP and complicate diagnosis, as clinical manifestations can resemble those of
Payman Sadeghi +5 more
wiley +1 more source
Teadenol A alleviates CUMS‐induced depressive behaviors by attenuating hippocampal neuronal damage, restoring metabolic homeostasis, and reshaping gut microbiota composition via the microbiota–gut–brain axis. ABSTRACT Depression is a chronic mental disorder that impacts human health.
Tiyue Zhao +10 more
wiley +1 more source
Probiotics Cancer Interaction, Prevention, and Therapy
ABSTRACT Cancer is a significant global health concern and ranks as the second most common cause of death on a worldwide scale. A combination of hereditary and lifestyle variables, such as diet, smoking, alcohol consumption, physical exercise, and the gut microbiota, impacts cancer development. Dysbiosis, an imbalance in gut microorganisms, can promote
Mostafa Saebi +7 more
wiley +1 more source
ABSTRACT Background and Aims Primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) represent a unique clinical syndrome affecting up to 80% of PSC patients, characterised by distinct epidemiological patterns, pathophysiological mechanisms and clinical outcomes that differ substantially from either condition occurring independently ...
Luisa Bertin +7 more
wiley +1 more source
Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis [PDF]
The goal of this investigation was to determine whether chenodeoxycholic acid (CDCA)-induced apoptosis is prevented by ursodeoxycholic acid (UDCA) or tauroursodeoxycholic acid (TUDC) and to characterize the involvement of mitochondria in the process ...
Rolo, Anabela P. +3 more
core +1 more source
Critical Review: The Past, Present, and Future of Small Intestinal Bacterial Overgrowth (SIBO)
ABSTRACT Small intestinal bacterial overgrowth (SIBO) has evolved from a severe debilitating illness to a clinical spectrum associated with abnormalities of microbial populations in the small intestine. It is best described as a pathophysiological state that may contribute to symptoms or other pathology in a wide range of gastrointestinal conditions ...
Ayesha Shah +2 more
wiley +1 more source
Влияние урсодезоксихолевой и тауроурсодезоксихолевой кислот на митохондриальное окисление и окислительное фосфорилирование у крыс, получавших метионин-холин дефицитную диету [PDF]
ТАУРОХОЛЕВАЯ КИСЛОТАУРСОДЕЗОКСИХОЛЕВАЯ КИСЛОТАМИТОХОНДРИАЛЬНЫЕ БОЛЕЗНИФОСФОРИЛИРОВАНИЕ ...
Буко, В. У. +1 more
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