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Intrahepatic cholestasis of pregnancy [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2007
Intrahepatic cholestasis of pregnancy (ICP) is a cholestatic disorder characterized by (i) pruritus with onset in the second or third trimester of pregnancy, (ii) elevated serum aminotransferases and bile acid levels, and (iii) spontaneous relief of ...
Beuers Ulrich, Pusl Thomas
doaj   +6 more sources

Intrahepatic cholestasis of pregnancy [PDF]

open access: yesРМЖ. Мать и дитя, 2019
P.V. Kozlov1, I.V. Samsonova2 1Pirogov Russian National Research Medical University, Moscow, Russian Federation 2City Clinical Hospital No. 52, Moscow, Russian Federation Intrahepatic cholestasis of pregnancy (ICP) is a reversible form of ...
P.V. Kozlov, I.V. Samsonova
doaj   +5 more sources

Genome-wide meta-analysis identifies genetic drivers of bile acid metabolism in intrahepatic cholestasis of pregnancy [PDF]

open access: yesNature Communications
Intrahepatic cholestasis of pregnancy, which affects 0.2–2% of pregnancies, is characterized by pruritus, increased aminotransferase activity and elevated serum bile acids. Previous studies have implicated liver-enriched genes in intrahepatic cholestasis
Jaakko S. Tyrmi   +33 more
doaj   +3 more sources

Intrahepatic cholestasis of pregnancy [PDF]

open access: yesWorld Journal of Gastroenterology, 2009
Intrahepatic cholestasis of pregnancy is the most common pregnancy-specific liver disease that typically presents in the third trimester. The clinical features are maternal pruritus in the absence of a rash and deranged liver function tests, including raised serum bile acids. Intrahepatic cholestasis of pregnancy is associated with an increased risk of
Williamson, Catherine, Geenes, Victoria
openaire   +5 more sources

Congenital thrombophilia associated with intrahepatic cholestasis of pregnancy. A case report [PDF]

open access: yesFolia Medica, 2022
Intrahepatic cholestasis of pregnancy is pregnancy-specific liver disorder, characterized by pruritus as the main clinical symptom, and fasting liver function tests.
Corina Iliadi-Tulbure   +4 more
doaj   +4 more sources

Intrahepatic Cholestasis of Pregnancy [PDF]

open access: yesGeburtshilfe und Frauenheilkunde, 2021
AbstractIntrahepatic cholestasis of pregnancy (ICP) is a rare but potentially serious complication of pregnancy, the main symptom of which is intense pruritus with elevated serum levels of bile acids. The elevated serum bile acid concentration is regarded as a predictor for poor perinatal outcome including intrauterine death. Ursodeoxycholic acid (UDCA)
Jurk, Stanisław M.   +2 more
openaire   +4 more sources

EVALUATION OF RISK FACTORS FOR INTRAHEPATIC CHOLESTASIS OF PREGNANCY IN PATIENTS PRESENTING TO A TERTIARY CARE CENTRE

open access: yesPakistan Armed Forces Medical Journal, 2021
Objectives: To evaluate the principal risk factors associated with development of intrahepatic cholestasis of pregnancy (ICP) in patients presenting to a tertiary care hospital. Study Design: Case control study.
Rabiah Anwar   +5 more
doaj   +3 more sources

Intrahepatic cholestasis of pregnancy and theory of inheritance of the disease. Literature review

open access: yesThe Journal of Maternal-Fetal & Neonatal Medicine, 2023
Intrahepatic cholestasis during pregnancy is associated with a higher risk of prenatal and maternal complications. There are several new publications and guidelines on the detection and thresholds of intrahepatic cholestasis during pregnancy.
Weronika Niemyjska-Dmoch   +4 more
doaj   +1 more source

Intrahepatic Cholestasis of Pregnancy [PDF]

open access: yesClinical Obstetrics & Gynecology, 2020
Intrahepatic cholestasis of pregnancy is a common disorder of pregnancy manifested by pruritus and elevated bile acids. The etiology of cholestasis is poorly understood and management is difficult due to the paucity of data regarding its diagnosis, treatment, and related adverse outcomes.
Devin D, Smith, Kara M, Rood
openaire   +3 more sources

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

open access: yesHepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu   +20 more
wiley   +1 more source

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