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Intrahepatic Cholestasis of Pregnancy [PDF]

open access: yesBMJ, 2016
#### What you need to know A 30 year old, 35 week pregnant, nulliparous woman visits her general practitioner because of itching but no rash. Fundal height measurements and fetal movements are normal. The GP arranges an urgent antenatal clinic review, where liver function tests (LFTs), including bile acids, are reported as normal.
Ovadia, Caroline, Williamson, Catherine
core   +3 more sources

Congenital thrombophilia associated with intrahepatic cholestasis of pregnancy. A case report [PDF]

open access: yesFolia Medica, 2022
Intrahepatic cholestasis of pregnancy is pregnancy-specific liver disorder, characterized by pruritus as the main clinical symptom, and fasting liver function tests.
Corina Iliadi-Tulbure   +4 more
doaj   +3 more sources

Distribution of endotoxin in maternal and fetal body with intrahepatic cholestasis of pregnancy and its association with adverse fetal outcome

open access: yesBMC Pregnancy and Childbirth, 2022
Background Intrahepatic cholestasis of pregnancy is a pregnancy-specific liver disease. In this study, we sought to explore the distribution of lipopolysaccharide in the maternal body, and its effect on the fetal body in the intrahepatic cholestasis of ...
Xiaomei Huang   +3 more
doaj   +1 more source

Intrahepatic Cholestasis of Pregnancy [PDF]

open access: yesGeburtshilfe und Frauenheilkunde, 2021
AbstractIntrahepatic cholestasis of pregnancy (ICP) is a rare but potentially serious complication of pregnancy, the main symptom of which is intense pruritus with elevated serum levels of bile acids. The elevated serum bile acid concentration is regarded as a predictor for poor perinatal outcome including intrauterine death. Ursodeoxycholic acid (UDCA)
Jurk, Stanisław M.   +2 more
openaire   +2 more sources

A novel homozygous mutation in the USP53 gene as the cause of benign recurrent intrahepatic cholestasis in children: a case report

open access: yesThe Turkish Journal of Pediatrics, 2023
Background. Benign recurrent intrahepatic cholestasis (BRIC) is a rare cause of cholestasis with recurrent episodes of jaundice and pruritus without extrahepatic bile duct obstruction.
Burcu Berberoğlu Ateş   +5 more
doaj   +1 more source

Intrahepatic cholestasis of pregnancy [PDF]

open access: yesWorld Journal of Gastroenterology, 2009
Intrahepatic cholestasis of pregnancy is the most common pregnancy-specific liver disease that typically presents in the third trimester. The clinical features are maternal pruritus in the absence of a rash and deranged liver function tests, including raised serum bile acids. Intrahepatic cholestasis of pregnancy is associated with an increased risk of
Williamson, Catherine, Geenes, Victoria
openaire   +4 more sources

Effects of cytomegalovirus infection on the differential diagnosis between biliary atresia and intrahepatic cholestasis in a Chinese large cohort study

open access: yesAnnals of Hepatology, 2021
Introduction and objectives: Differentiating biliary atresia from other causes of neonatal cholestasis is challenging, particularly when cytomegalovirus (CMV) and biliary atresia occur simultaneously.
Dongying Zhao   +6 more
doaj   +1 more source

INTRAHEPATIC CHOLESTASIS IN PREGNANCY [PDF]

open access: yesPraxis medica, 2013
<p>Abnormal liver function tests occur in 3-5% of pregnancies, with many potential causes, including coincidental liver disease (most commonly viral hepatitis or gallstones) and underlying chronic liver disease. Pruritus in pregnancy is common, affecting 23% of pregnancies, of which a small proportion will have obstetric cholestasis ...
Savić Ž.   +5 more
openaire   +2 more sources

Da-Chai-Hu-Tang Protects From Acute Intrahepatic Cholestasis by Inhibiting Hepatic Inflammation and Bile Accumulation via Activation of PPARα

open access: yesFrontiers in Pharmacology, 2022
Cholestasis is caused by intrahepatic retention of excessive toxic bile acids and ultimately results in hepatic failure. Da-Chai-Hu-Tang (DCHT) has been used in China to treat liver and gallbladder diseases for over 1800 years. Here, we demonstrated that
Shihao Xu   +16 more
doaj   +1 more source

Compound Heterozygous MYO5B Mutation, a Cause of Infantile Cholestasis: A Case Report

open access: yesJournal of Nepal Medical Association, 2022
Infantile cholestasis is a common clinical problem in early infancy characterised by impairment in bile formation and/or flow. It requires prompt evaluation for underlying aetiology to initiate appropriate management.
Muna Khanal   +2 more
doaj   +1 more source

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