Results 31 to 40 of about 51,796 (192)

A child with debilitating pruritus

Clinics and Practice, 2016
We describe a case of two-year-old boy presenting with debilitating pruritus, patchy alopecia and jaundice since the age of 6 months. On evaluation he had intrahepatic cholestasis with persistently raised serum alkaline phosphatase, normal Gamma glutamyl
Nikhil Sonthalia, Sami S. Jain, Vinay B. Pawar, Vinay G. Zanwar, Ravindra G. Surude, Pravin M. Rathi, Kshitij K. Munde, Sandeep Bavdekar   +7 more
doaj   +1 more source

A patient with obstructive jaundice secondary to intrahepatic bleeding caused by prostate cancer metastasis

Urology Case Reports, 2021
A metastatic disease causes jaundice is not uncommon and usually related to direct tumor invasion to the biliary tree or massive intrahepatic metastasis.
Essa A. Adawi
doaj   +1 more source

A frequent variant in the human bile salt export pump gene ABCB11 is associated with hepatitis C virus infection, but not liver stiffness in a German population [PDF]

, 2012
Background: The human ATP-binding cassette, subfamily B, member 11 (ABCB11) gene encodes the bile salt export pump, which is exclusively expressed at the canalicular membrane of hepatocytes.
Müllenbach, Roman, Marcin Krawczyk, Weber, Susanne N., Grünhage, Frank, Sarrazin, Christoph, Zimmer, Vincent, Frank Grünhage, Krawczyk, Marcin, Lammert, Frank, Christoph Sarrazin, Roman Müllenbach, Susanne N Weber, Vincent Zimmer, Frank Lammert   +13 more
core   +2 more sources

Intrahepatic Cholestasis of Pregnancy [PDF]

, 2016
Intrahepatic cholestasis of pregnancy, also known as obstetric cholestasis, is a pruritic condition of pregnancy, characterized by an underlying elevation in circulating bile acids and liver derangement, and associated with adverse fetal outcomes, such ...
Ovadia, Caroline; id_orcid, Williamson, Catherine   +1 more
core   +1 more source

New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical Implications

Canadian Journal of Gastroenterology and Hepatology, 2018
Cholestasis is characterised by impaired bile secretion and accumulation of bile salts in the organism. Hereditary cholestasis is a heterogeneous group of rare autosomal recessive liver disorders, which are characterised by intrahepatic cholestasis ...
Eva Sticova, Milan Jirsa, Joanna Pawłowska   +2 more
doaj   +1 more source

Perinatal outcomes of intrahepatic cholestasis during pregnancy: An 8-year case-control study.

PLoS ONE, 2020
INTRODUCTION:Previous studies of fetal effects have suggested that intrahepatic cholestasis of pregnancy is associated with a higher rate of adverse neonatal outcomes including preterm birth, neonatal respiratory distress syndrome, meconium-stained ...
Chloé Arthuis, Caroline Diguisto, Henri Lorphelin, Vincent Dochez, Emmanuel Simon, Franck Perrotin, Norbert Winer   +6 more
doaj   +1 more source

Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?

Gynecology Obstetrics & Reproductive Medicine, 2021
OBJECTIVES: We aimed to determine whether mean platelet volume value and/or neutrophil/lymphocyte ratio values are useful as a predictive marker for gestational cholestasis.
Hasan Eroglu, Harun Egemen Tolunay, Kemal Sarsmaz, Gokcen Orgul, Dilek Sahin, Aykan Yucel   +5 more
doaj   +1 more source

The prevalence and pregnancy outcomes of intrahepatic cholestasis of pregnancy: a retrospective clinical audit review

, 2018
Background To determine the prevalence and outcomes of intrahepatic cholestasis of pregnancy. Methods A review comparing intrahepatic cholestasis of pregnancy pregnancies to all other pregnancies in three tertiary care Australian hospitals over a 36 ...
Morton, Adam, McCuaig, Ruth, Arthur, Chris, Carins, Thomas, Gardiner, Fergus W, Laurie, Josephine, Peek, Michael J., Peek, Michael J, Gardiner, Fergus W., Lim, Boon, Neeman, Teresa   +10 more
core   +1 more source

Intrahepatic Cholestasis of Pregnancy

, 2014
Intrahepatic cholestasis of pregnancy is the most common pregnancy-specific liver disease that typically presents in the third trimester. The clinical features are maternal pruritus in the absence of a rash and deranged liver function tests, including ...
Geenes, Victoria, Williamson, Catherine
core   +1 more source

Assessment of aspartate aminotransferase to Platelet Ratio Index and Fibrosis-4 Index score on women with intrahepatic cholestasis of pregnancyAJOG Global Reports at a Glance

AJOG Global Reports
BACKGROUND: Intrahepatic cholestasis of pregnancy is a pregnancy-related liver condition that is characterized by elevated liver function tests and/or bile acids in the presence of pruritis.
Maria Cemortan, PhD, Corina Iliadi-Tulbure, PhD, Irina Sagaidac, PhD, Olga Cernetchi, PhD   +3 more
doaj   +1 more source