Results 31 to 40 of about 28,196 (246)

Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s Disease

open access: yesCase Reports in Hematology, 2015
Intrahepatic cholestasis in the form of paraneoplastic phenomena is an uncommon presentation of Hodgkin’s lymphoma (HL). Herein we report the diagnosis of mixed type HL-related idiopathic intrahepatic cholestasis in a 73-year-old man presenting with ...
Hande Atalay   +6 more
doaj   +1 more source

A child with debilitating pruritus

open access: yesClinics and Practice, 2016
We describe a case of two-year-old boy presenting with debilitating pruritus, patchy alopecia and jaundice since the age of 6 months. On evaluation he had intrahepatic cholestasis with persistently raised serum alkaline phosphatase, normal Gamma glutamyl
Nikhil Sonthalia   +7 more
doaj   +1 more source

A patient with obstructive jaundice secondary to intrahepatic bleeding caused by prostate cancer metastasis

open access: yesUrology Case Reports, 2021
A metastatic disease causes jaundice is not uncommon and usually related to direct tumor invasion to the biliary tree or massive intrahepatic metastasis.
Essa A. Adawi
doaj   +1 more source

A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. [PDF]

open access: yes, 2019
Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies.
Apostol, George   +15 more
core   +2 more sources

Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?

open access: yesGynecology Obstetrics & Reproductive Medicine, 2021
OBJECTIVES: We aimed to determine whether mean platelet volume value and/or neutrophil/lymphocyte ratio values are useful as a predictive marker for gestational cholestasis.
Hasan Eroglu   +5 more
doaj   +1 more source

Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholagnitis [PDF]

open access: yes, 2018
The non-invasive differentiation of malignant and benign biliary disease is a clinical challenge. Carbohydrate antigen 19-9 (CA19-9), leucine-rich α2-glycoprotein (LRG1), interleukin 6 (IL6), pyruvate kinase M2 (PKM2), cytokeratin 19 fragment (CYFRA21.1)
Blyuss, O   +9 more
core   +2 more sources

New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical Implications

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2018
Cholestasis is characterised by impaired bile secretion and accumulation of bile salts in the organism. Hereditary cholestasis is a heterogeneous group of rare autosomal recessive liver disorders, which are characterised by intrahepatic cholestasis ...
Eva Sticova   +2 more
doaj   +1 more source

Perinatal outcomes of intrahepatic cholestasis during pregnancy: An 8-year case-control study.

open access: yesPLoS ONE, 2020
INTRODUCTION:Previous studies of fetal effects have suggested that intrahepatic cholestasis of pregnancy is associated with a higher rate of adverse neonatal outcomes including preterm birth, neonatal respiratory distress syndrome, meconium-stained ...
Chloé Arthuis   +6 more
doaj   +1 more source

Case Report: A Rare Heterozygous ATP8B1 Mutation in a BRIC1 Patient: Haploinsufficiency?

open access: yesFrontiers in Medicine, 2022
Benign recurrent intrahepatic cholestasis (BRIC) is an autosomal recessive disorder characterized by recurrent cholestasis. ATPase class I, type 8B, member 1 (ATP8B1) encodes familial intrahepatic cholestasis 1 (FIC1), which acts as a phosphatidylserine ...
Hao Bing   +5 more
doaj   +1 more source

Evaluation of the protective effect curcumin on encephalopathy caused by intrahepatic and extrahepatic damage in male rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2021
Objective(s): Along with increased intracranial pressure (ICP) and brain damage, brain edema is the most common cause of death in patients with hepatic encephalopathy.
Forouzan Frozandeh   +6 more
doaj   +1 more source

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