Results 191 to 200 of about 20,067 (234)
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Solubilization of oleanolic acid and ursolic acid by cosolvency
Archives of Pharmacal Research, 1997Solubilities of oleanolic acid and ursolic acid in aqueous surfactant solutions, liquid polyethylene glycols (PEG), and solvents of various polarity were measured. The results showed that the solutes were slightly or moderately solubilized in the surfactant solutions and the liquid PEGs.
I J, Jin, Y I, Ko, Y M, Kim, S K, Han
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The cytotoxic activity of ursolic acid derivatives
European Journal of Medicinal Chemistry, 2005Ursolic acid and 2alpha-hydroxyursolic acid isolated from apple peels were found to show growth inhibitory activity against four tumor cell lines, HL-60, BGC, Bel-7402 and Hela. Structural modifications were performed on the C-3, C-28 and C-11 positions of ursolic acid and the cytotoxicity of the derivatives was evaluated.
Chao-Mei, Ma +6 more
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Oxidation of ursolic acid by ozone
Chemistry of Natural Compounds, 2011Oxidation of methyl esters of ursolic and 3-acetoxyursolic acids by ozone formed products with a 12-oxo11S,13R-oxetane moiety on ring C.
O. B. Kazakova +4 more
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Ursolic acid: An anti‐ and pro‐inflammatory triterpenoid
Molecular Nutrition & Food Research, 2008AbstractThere is growing interest in the elucidation of the biological functions of triterpenoids, ubiquitously distributed throughout the plant kingdom, some of which are used as anticancer and anti‐inflammatory agents in Asian countries. Ursolic acid (UA), a natural pentacyclic triterpenoid carboxylic acid, is the major component of some traditional ...
Yasutaka, Ikeda +2 more
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Ursolic Acid Prevents Retinoic Acid-Induced Bone Loss in Rats
Chinese Journal of Integrative Medicine, 2018To examine the effects of ursolic acid (UA) on mitigating retinoic acid (RA)-induced osteoporosis in rats.Fifty female Sprague-Dawley rats were randomly divided into the control group (n=10) and the osteoporosis group (n=40). The 40 osteoporosis rats were induced by 75 mg/(kg•d) RA once daily for 2 weeks, and then were randomly assigned to vehicle ...
Min, Cheng +5 more
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Structure of ursolic acid ethanol solvate
Acta Crystallographica Section C Crystal Structure Communications, 1992C 30 H 48 O 3 .C 2 H 6 O cristallise dans P2 1 2 1 2 1 avec a = 7,199, b = 12,157 et c = 33,888 A, Z = 4; affinement jusqu'a R = 0,050. Les cycles adoptent des conformations chaise. La cohesion cristalline est assuree par un reseau de contacts de van der Waals et de liaisons hydrogene avec les molecules ethanol.
A. Simon +5 more
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Biosynthesis of ursolic acid-2-14C
Phytochemistry, 1967Abstract Ursolic acid- 14 C was prepared by administration of mevalonic acid-2- 14 C, sodium acetate-1- and -2- 14 C, sodium formate- 14 C and l -methionine-methyl- 14 C respectively to cut sections of Salvia officinalis . Only mevalonic acid-2- 14 C was incorporated efficiently into the acidic triterpene.
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