Results 51 to 60 of about 5,145,076 (274)

Regulation of mitogen-activated protein kinase signaling pathway and proinflammatory cytokines by ursolic acid in murine macrophages infected with Mycobacterium avium

Infectious Disease Reports, 2020
Mycobacterium avium, one of the closest relatives of Mycobacterium tuberculosis (MTB), offers an advantage in studying MTB because of its tuberculosis-like effect in humans and host immune tolerance.
Dian Ayu Eka Pitaloka, Andrea M. Cooper, Aluicia Anita Artarini, Elin Yulinah Sukandar, Sophi Damayanti   +4 more
doaj   +1 more source

Bioactivity-Guided Investigation of the Anti-Inflammatory Activity of Hippophae rhamnoides Fruits [PDF]

, 2017
According to modern ethnobotanical records, the fruit of Hippophae rhamnoides is effective in the treatment of different allergic symptoms. In order to obtain pharmacological evidence for this observation, the fruit was investigated for anti-inflammatory
Blazsó, Gábor, Hohmann, Judit, Jedlinszki, Nikoletta, Kúsz, Norbert, Rédei, Dóra, Zupkó, István   +5 more
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Preclinical Assessment of Ursolic Acid Loaded into Nanostructured Lipid Carriers in Experimental Visceral Leishmaniasis

Pharmaceutics, 2021
Ursolic acid, a triterpene produced by plants, displayed leishmanicidal activity in vitro and in vivo; however, the low solubility of this triterpene limits its efficacy.
J. Jesus, I. Sousa, T. N. F. da Silva, Aurea F. Ferreira, M. Laurenti, L. Antonangelo, C. Faria, Paulo Cardoso da Costa, Domingos de Carvalho Ferreira, L. Passero   +9 more
semanticscholar   +1 more source

Enhanced Antioxidant Activity of Ursolic Acid by Complexation with Copper (II): Experimental and Theoretical Study

Materials, 2021
The copper (II) complex of ursolic acid (Cu(II) UA) was synthesized and discussed in terms of its infrared, UV–visible spectra, quantum-chemical calculations at B3LYP/6-31G(d) level and antioxidant capacity.
M. Samsonowicz, M. Kalinowska, Kamila Gryko   +2 more
semanticscholar   +1 more source

Antibacterial and Antioxidant Activities of Ursolic Acid and Derivatives

Molecules, 2014
Ursolic acid, an important bioactive compound, was isolated from ethanol extract of aerial parts of Sambucus australis. In order to develop bioactive ursolic acid derivatives, two semi-synthetic compounds were obtained through modification at C-3.
Patrícia G.G. do Nascimento, Telma L.G. Lemos, Ayla M.C. Bizerra, Ângela M.C. Arriaga, Daniele A. Ferreira, Gilvandete M.P. Santiago, Raimundo Braz-Filho, José Galberto M. Costa   +7 more
doaj   +1 more source

Differential Anti-Proliferative and Anti-Migratory Activities of Ursolic Acid, 3-O-Acetylursolic Acid and Their Combination Treatments with Quercetin on Melanoma Cells

Biomolecules, 2020
We evaluate how 3-acetylation modulates the in vitro activity of ursolic acid in melanoma cells alone or in combination treatments with quercetin. Anti-proliferative studies on A375 cells and adult human dermal fibroblasts included analyses on cell cycle
Aljawharah AlQathama, Luying Shao, Ammar Bader, Proma Khondkar, Simon Gibbons, Jose M Prieto   +5 more
doaj   +1 more source

Counter-current chromatography for the separation of terpenoids: A comprehensive review with respect to the solvent systems employed [PDF]

, 2014
Copyright @ 2014 The Authors.This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.Natural ...
A Berthod, A Berthod, A Koch, A Li, A Marston, A Maurya, A Peng, A Sun, ALM Nasser, AM Martin, AS Engelberth, AS Graham, B Diallo, B Diallo, B Medhi, B Pinel, BCB dos Santos, BK Gosse, C Zhao, CR Cheng, D Agostinho, D Du, D Fisher, D Grancher, D Wang, D Wang, D Wu, D Zhao, E Mudge, F Chen, F Chen, F Chen, F Fullas, F Gutiérrez, F He, F Oka, F Qiu, F Xiang, F Yang, G Tian, G Tian, G Wang, G Yan, GD Brown, GG Rocha, H Knapp, H Wu, H Ye, H Ye, H Zhang, HB Li, HB Li, HB Li, HB Li, HT Lu, I Slacanin, IA Sutherland, IA Sutherland, IA Sutherland, Ian Garrard, IJ Garrard, IJ Garrard, IJ Garrard, IJ Ha, J Hu, J Huang, J Liang, J Liu, J Ma, J Peng, J Wang, J Wang, J Wang, J Xie, J Xie, J Xu, J Yan, JCT Silva, JH Lee, JP Fan, JT Fischedick, JT Fischedick, JT Fischedick, K Skalicka-Woźniak, KD Yoon, KD Yoon, Krystyna Skalicka-Woźniak, KY Yoo, M Gu, M Gu, M Hamzaoui, M Lechtenberg, M Liu, M Puertas Mejia, MP Gasper, N Acton, N Fischer, N Frighetto, O Shehzad, O Shehzad, O Shehzad, O Shirota, O Shirota, P Hewitson, PA Souza De, PK Ajikumar, Q Chen, Q Du, Q Du, Q Du, Q Du, Q Du, Q Du, Q Du, QB Han, QB Han, QB Han, R Aman, R Graziose, R Roscher, R Tsao, RTS Frighetto, S Baldermann, S Baldermann, S He, S Liu, S Shi, S Wu, S Wu, S Yao, S Yao, SM Kim, SS Cicek, SY Shi, T Abbott, VF Rodrigues, VGP Severino, VP da Silva, W He, X Cao, X Han, X Qi, X Shi, X Xiao, X Xin, XC Li, XH Xiao, XY Huang, Y Cheng, Y Cheng, Y Geng, Y Ikai, Y Ito, Y Ito, Y Ito, Y Ito, Y Jiang, Y Lu, Y Lu, Y Ma, Y Wang, Y Wei, Y Wei, Y Wei, Y Yang, Y Yang, Y Yuan, Y Zhang, Y Zhao, YW Ha, YW Ha, YY Dang, Z Jiang   +172 more
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Ursolic acid in health and disease

The Korean Journal of Physiology & Pharmacology, 2018
Ursolic acid (UA) is a natural triterpene compound found in various fruits and vegetables. There is a growing interest in UA because of its beneficial effects, which include anti-inflammatory, anti-oxidant, anti-apoptotic, and anti-carcinogenic effects.
Seo, Dae Yun, Lee, Sung Ryul, Heo, Jun-Won, No, Mi-Hyun, Rhee, Byoung Doo, Ko, Kyung Soo, Kwak, Hyo-Bum, Han, Jin   +7 more
openaire   +2 more sources

Therapeutic effect of ursolic acid on fetal development in pregnant rats with gestational diabetes mellitus via AGEs-RAGE signaling pathway.

Journal of food biochemistry, 2021
To investigate the effect of ursolic acid on the fetal development of gestational diabetes mellitus (GDM) caused by streptozotocin (STZ) and explore the potential mechanism for it.
Senge Dai, Xiaoyan Meng, Xiaqin Cai, Chun-Hsien Yuan, Zhongmei Zhao, Li Zhong, Yongmei Shi, Fengling Yin   +7 more
semanticscholar   +1 more source

Ursolic acid inhibits superoxide production in activated neutrophils and attenuates trauma-hemorrhage shock-induced organ injury in rats.

PLoS ONE, 2014
Neutrophil activation is associated with the development of organ injury after trauma-hemorrhagic shock. In the present study, ursolic acid inhibited the superoxide anion generation and elastase release in human neutrophils.
Tsong-Long Hwang, Hsin-I Shen, Fu-Chao Liu, Hsin-I Tsai, Yang-Chang Wu, Fang-Rong Chang, Huang-Ping Yu   +6 more
doaj   +1 more source