Systemic Mastocytosis: Predominantly Involving the Bone, A Case Report [PDF]
Systemic mastocytosis (SM) is a rare clonal disorder of mast cells that can range from chronic smouldering type to aggressive mast cell leukaemia. It presents with non–specific symptoms like urticaria pigmentosa, unexplained flushing, hypotension and ...
Ketan P Mallya +4 more
doaj +1 more source
Relationship of chronic marginal periodontitis (alveolar pyorrhea) to histamine [PDF]
1. Considering an imaginable important role of histamine in inflammations or allergic reactions, some clinical and experimental studies were made for the purpose of findings the relationship of the pathological changes of A. P. to local histamine.
Fujioka, Yukio
core +1 more source
Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence
ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab +4 more
wiley +1 more source
SEVERE OSTEOPOROSIS DUE TO SYSTEMIC MAST CELL DISEASE: SUCCESSFUL TREATMENT WITH INTERFERON ALPHA-2B [PDF]
We describe a 33-yr-old man suffering from severe vertebral osteoporosis and urticaria pigmentosa due to systemic mast cell disease (SMCD). Because i.v.
BEYELER, C. +7 more
core
Clinical practice guidelines for the diagnosis and treatment of scabies
Abstract Scabies, caused by the Sarcoptes scabiei var hominis mite burrowing into the skin, is a highly contagious disease characterized by intense nocturnal itching. Its global impact is considerable, affecting more than 200 million individuals annually and posing significant challenges to healthcare systems worldwide.
Soner Uzun +24 more
wiley +1 more source
Cutaneous Mastocytosis in Childhood. Retrospective Study of 32 Patients [PDF]
Introdução: A designação de mastocitose engloba várias entidades clinicamente distintas caracterizadas pela acumulação tissular de mastócitos. A pele é o órgão mais frequentemente envolvido.
Amaro, C +4 more
core
Subcellular expression of CD30 in cutaneous mastocytosis—An important factor for targeted treatment
Abstract Background The subcellular distribution of CD30 on mast cells and the presence of eosinophils in cutaneous mastocytosis require further investigation, especially as the cell surface expression of CD30 is critical for the therapeutic response of systemic mastocytosis to brentuximab vedotin.
Christina Mitteldorf +4 more
wiley +1 more source
Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors [PDF]
OBJECTIVES: To characterise the clinical features, immune manifestations and molecular mechanisms in a recently described autoinflammatory disease caused by mutations in TRNT1, a tRNA processing enzyme, and to explore the use of cytokine inhibitors in ...
et al +3 more
core +1 more source
Dermatoscopy in diagnosing maculopapular cutaneous mastocytosis [PDF]
The diagnosis of cutaneous mastocytosis is based on the clinical finding of the pigmented macules or papules, positive Darier's sign and a dermal infiltrate composed of mast cells that can be better visualized by the use of special stains (Giemsa or ...
Popadić Mirjana
doaj +1 more source
ABSTRACT Background Spinal adhesive arachnoidopathy (SAA) is a chronic pathology associated with persistent inflammatory responses in the arachnoid. Adhesive arachnoiditis (AA) is one of the major forms of SAA, with accompanying secondary complications.
Weikang Zhang +8 more
wiley +1 more source

