Results 61 to 70 of about 3,759 (229)

Systemic Mastocytosis: Predominantly Involving the Bone, A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2013
Systemic mastocytosis (SM) is a rare clonal disorder of mast cells that can range from chronic smouldering type to aggressive mast cell leukaemia. It presents with non–specific symptoms like urticaria pigmentosa, unexplained flushing, hypotension and ...
Ketan P Mallya, Sushma Belurkar, Annamma Kurian, Laxmi Rao, Bikash Singhania   +4 more
doaj   +1 more source

Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors [PDF]

, 2018
OBJECTIVES: To characterise the clinical features, immune manifestations and molecular mechanisms in a recently described autoinflammatory disease caused by mutations in TRNT1, a tRNA processing enzyme, and to explore the use of cytokine inhibitors in ...
et al, Giannelou, Angeliki, Pachlopnik, Jana M, Prader, Seraina   +3 more
core   +1 more source

Clinical practice guidelines for the diagnosis and treatment of scabies

International Journal of Dermatology, Volume 63, Issue 12, Page 1642-1656, December 2024.
Abstract Scabies, caused by the Sarcoptes scabiei var hominis mite burrowing into the skin, is a highly contagious disease characterized by intense nocturnal itching. Its global impact is considerable, affecting more than 200 million individuals annually and posing significant challenges to healthcare systems worldwide.
Soner Uzun, Murat Durdu, Aslan Yürekli, Mehmet K. Mülayim, Melih Akyol, Sevtap Velipaşaoğlu, Mehmet Harman, Ayşegül Taylan‐Özkan, Ekin Şavk, Devrim Demir‐Dora, Levent Dönmez, Umut Gazi, Habibullah Aktaş, Aysun Ş. Aktürk, Gülay Demir, Fatih Göktay, Mehmet S. Gürel, Neşe G. Gürok, Ayşe S. Karadağ, Özlem S. Küçük, Çağrı Turan, Müge G. Ozden, Zeynep K. Ural, Orçun Zorbozan, Kosta Y. Mumcuoğlu   +24 more
wiley   +1 more source

Cutaneous Mastocytosis in Childhood. Retrospective Study of 32 Patients [PDF]

, 2012
Introdução: A designação de mastocitose engloba várias entidades clinicamente distintas caracterizadas pela acumulação tissular de mastócitos. A pele é o órgão mais frequentemente envolvido.
Amaro, C, Cardoso, J, Coelho Macias, V, Freitas, I, Vieira, R   +4 more
core  

Subcellular expression of CD30 in cutaneous mastocytosis—An important factor for targeted treatment

Journal of Cutaneous Pathology, Volume 51, Issue 11, Page 881-892, November 2024.
Abstract Background The subcellular distribution of CD30 on mast cells and the presence of eosinophils in cutaneous mastocytosis require further investigation, especially as the cell surface expression of CD30 is critical for the therapeutic response of systemic mastocytosis to brentuximab vedotin.
Christina Mitteldorf, Aleksandra Kulberg, Michael Tronnier, Michael P. Schön, Werner Kempf   +4 more
wiley   +1 more source

Spinal Adhesive Arachnoidopathy, the Disorder More Than Simply Adhesive Arachnoiditis: A Comprehensive Systematic Review of 510 Cases

CNS Neuroscience &Therapeutics, Volume 30, Issue 10, October 2024.
ABSTRACT Background Spinal adhesive arachnoidopathy (SAA) is a chronic pathology associated with persistent inflammatory responses in the arachnoid. Adhesive arachnoiditis (AA) is one of the major forms of SAA, with accompanying secondary complications.
Weikang Zhang, Zhenlei Liu, Kai Wang, Lei Zhang, Shaocheng Liu, Xiangyu Zhang, Yutian Wang, Kun He, Hao Wu   +8 more
wiley   +1 more source

Erhöhte basale Serumtryptasekonzentration oder Mastozytose als Risikofaktor der Hymenopterengiftallergie Leitlinie der Deutschen Gesellschaft für Allergologie und Klinische Immunologie (DGAKI) (AWMF-Leitlinie 061/018) [PDF]

, 2017
Hymenopterengift-allergische Patienten mit Mastzellerkrankung, das heißt Mastozytose und/oder erhöhtem basalen Serumtryptasespiegel, haben ein hohes Risiko schwerer, lebensbedrohender Stichreaktionen.
Jarisch, Reinhart, Müller, Ulrich, Przybilla, Bernhard, Ruëff, Franziska   +3 more
core  

Diagnosis of systemic mastocytosis with cryptic deletion of TET2 and DNMT3A resulting from unbalanced translocation

British Journal of Haematology, Volume 205, Issue 3, Page 961-966, September 2024.
Summary Systemic mastocytosis (SM) is a rare haematological neoplasm associated with the gain of function mutation KIT D816V in 90% of adult patients. Classically, cytogenetic aberrations are not common except in cases of SM associated with another haematological neoplasm.
Signy Chow, Stephanie Lee, August Lin, Kenneth J. Craddock, Adam C. Smith, Hubert Tsui   +5 more
wiley   +1 more source

Childhood Pseudoxanthomatousmastocytosis; Report of two cases

Indian Journal of Dermatopathology and Diagnostic Dermatology, 2018
Cutaneous mastocytosis (CM) is a mast cell proliferative disorder that commonly affects pediatric population. It has various clinical forms such as urticaria pigmentosa, solitary mastocytoma, telangiectasia macularis eruptiva perstans, diffuse CM, and ...
Bhabani S. T. P. Singh, Tapaswini Tripathy, Bikash Ranjan Kar, Surabhi Singh   +3 more
doaj   +1 more source

Dermatoscopy in diagnosing maculopapular cutaneous mastocytosis [PDF]

Praxis Medica, 2016
The diagnosis of cutaneous mastocytosis is based on the clinical finding of the pigmented macules or papules, positive Darier's sign and a dermal infiltrate composed of mast cells that can be better visualized by the use of special stains (Giemsa or ...
Popadić Mirjana
doaj   +1 more source