Results 231 to 240 of about 391,908 (294)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Participatory co-design of pediatric rehabilitation technologies: a practice-based perspective. [PDF]

Front Med (Lausanne)
Melamed Yekel A, Gefen N, Weiss PL.
europepmc   +1 more source

Feasibility, Usability, and Acceptability of an Adaptive Mobile Health Medication Adherence Intervention for Youth: Iterative Mixed Methods Human-Centered Design Study. [PDF]

JMIR Form Res
Sayegh CS, Wu S, Lopez S, Dews A, Fleming J, Cortez D, Portillo J, Menendez T, Belzer M, West AE.   +9 more
europepmc   +1 more source

Japanese Health Information Technology Usability Evaluation Scale for Sexually Transmitted Infection-Related Chatbots: Development and Psychometric Validation Study. [PDF]

JMIR Hum Factors
Hato T, Ishikawa H, Todo K, Harada K, Yoshikawa A, Fukuda Y, Schnall R.   +6 more
europepmc   +1 more source

Adaptation of Social Health Care Tools From Paper-Based to Web-Based Formats: Scoping Review. [PDF]

Online J Public Health Inform
Dupont C, Savolainen E, Fjällström P, Eneslätt M.   +3 more
europepmc   +1 more source

A user centered evaluation framework for mobile health applications using Fuzzy AHP and TOPSIS: evidence from expert reviews and user experience data. [PDF]

Front Public Health
Huang X, Ma K.
europepmc   +1 more source

Investigating the Usability of a Multidimensional Metaverse Rehabilitation Platform for Survivors of Colorectal Cancer: Mixed Research Design Experiment. [PDF]

JMIR Serious Games
Hu Y, Ruan Z, Peng H, Huang Z, Yu X, Cai L, Xiao Y, Chen B, Huang X, Sun Q, Zhuo H, Shen Q.   +11 more
europepmc   +1 more source

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Strategic usability

CHI '97 extended abstracts on Human factors in computing systems looking to the future - CHI '97, 1997
Usability may now be practised by a large number of software developers, but has yet to gain wide acceptance. Communicating the value of usability must happen across multiple levels of an organisation, and requires speaking several "languages". This practical, hands-on tutorial will cover techniques for convincing management or potential clients of the
Sarah A. Bloomer, Rachel Croft, Helen M. Kieboom   +2 more
openaire   +2 more sources