Results 61 to 70 of about 8,836,721 (323)
Finnish Journal of eHealth and eWelfare, 2016 This paper outlines a practical approach for enabling user-centric healthcare information systems development in large scale. The approach is especially powerful at the current stage of clinical informatics adoption by the leading countries which have ...
Janne Pitkänen, Matti Pitkäranta
doaj
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und PraxisA central requirement for the use of artificial intelligence (AI) in medicine is its explainability, i. e., the provision of addressee-oriented information about its functioning.
Manuela Marquardt +4 more
doaj +1 more source
The usability of usability guidelines
Proceedings of the 21st Annual Conference of the Australian Computer-Human Interaction Special Interest Group: Design: Open 24/7, 2009 This paper is challenging the usability of traditional usability guidelines. The claim is that guideline descriptions and explanations are not satisfactory. Analysis results demonstrate vagueness and are ambiguous in explanation. The aim of the paper is to propose a set of principles (meta-guidelines) to be used for improving the usability of ...
openaire +3 more sources
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
Don't forget your classics: Systematizing 45 years of Ancestry for Security API Usability Recommendations [PDF]
arXiv, 2021 Producing secure software is challenging. The poor usability of security APIs makes this even harder. Many recommendations have been proposed to support developers by improving the usability of cryptography libraries and APIs; rooted in wider best practice guidance in software engineering and API design.
arxiv
FEBS Letters, EarlyView.LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra +7 more
wiley +1 more source
Automated Usability Testing: Analysing Asia Web Sites [PDF]
International Conference on Business and Information 2012 (ICBI
2012), Faculty of Commerce and Management Studies of University of Kelaniya,
Sri Lanka, 2012 Web usability is continuing to be a pressing problem. For number of years researchers have been developed tools for doing automatic web usability testing. This study uses our own PHP, and MySQL based tool AWebHUT: Automated Web Homepage Usability Tester to evaluate web usability of full Dmoz (www.dmoz.org) Asia web sites (45126 on time stamp 2011-12-03
arxiv
Lessons from Usable ML Deployments and Application to Wind Turbine Monitoring [PDF]
arXiv, 2023 Through past experiences deploying what we call usable ML (one step beyond explainable ML, including both explanations and other augmenting information) to real-world domains, we have learned three key lessons. First, many organizations are beginning to hire people who we call ``bridges'' because they bridge the gap between ML developers and domain ...
arxiv