Results 111 to 120 of about 2,904,443 (296)
Multivariate analysis of trip-chaining behavior [PDF]
Trip-chaining behavior has generally been associated with various demographic characteristics of households and individuals. This includes households with children having more complex activity patterns, or those who are employed needing to conduct ...
Robert Noland, John V. Thomas
core
Locked in and left out: the "prison penalty" for implementation of evidence-based interventions
Background While the broader medical community grapples with the widely accepted notion that it takes an average of 17 years for research evidence to be incorporated into clinical practice, the implementation of evidence-based interventions in carceral ...
Justin Berk +2 more
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The Influence of Gadget Use on the Social and Emotional Behavior of Elementary School Students
This study aims to analyze the influence of gadget use on the social and emotional behavior of students at SD Negeri 019 Sagulung Batam. The study employed a mixed methods approach with a sequential explanatory design, in which quantitative data ...
Suci Purwaningsih +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Maternal prenatal substance use and behavior problems among children in the U.S.
Prenatal exposure to smoking and alcohol-use is found to be correlated with various adverse consequences for children, including behavior problems. However, it is not clear whether this relationship is an artifact of underlying confounding factors that ...
Sen, Bisakha, Swaminathan, Shailender
core
Hispanic problem behavior youth are at an increased risk of engaging in HIV risk behaviors, including low condom use. However, relatively little research has examined factors that affect condom use in this population.
Malcolm, Shandey +7 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Background Understanding the changes in smoking rate and try smoking rate among Beijing college students and middle school students from 2008 to 2014, and preliminarily evaluate the school tobacco control work efficiency.
Ying Sun, Jia Li Duan, Xiao Peng Zeng
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

