Results 91 to 100 of about 5,628,361 (283)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Racialized police use of force and birth outcomes. [PDF]
Soc Sci Med, 2023 Chegwin V +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Prohibition of the use of force and legality of humanitarian intervention
Acta Iuris Stetinensis, 2016 This article addresses the problem of the legality and legitimacy of humanitarian intervention in the light of contemporary international law and practice.
Tadeusz Gadkowski
doaj +1 more source
Forced motion of a probe particle near the colloidal glass transition
, 2004 We use confocal microscopy to study the motion of a magnetic bead in a dense colloidal suspension, near the colloidal glass transition volume fraction $\phi_g$.
A. C Levitt +9 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Empirical research of the role of international law in the work of the UN Security Council [PDF]
Zbornik Radova: Pravni Fakultet u Novom Sadu, 2020 Interest of international law scholars into an empirical research has increased in the last decade. This paper is an example of one such research.
Milić Tatjana M.
doaj
Using Biological Motion to Investigate Perceptual-Cognitive Expertise in Law Enforcement Use-of-Force Decisions. [PDF]
J Police Crim Psychol, 2023 Connelly ME, Suss J, Vangsness L.
europepmc +1 more source
A one-dimensional model for theoretical analysis of single molecule experiments
, 2006 In this paper we compare two polymer stretching experiments. The outcome of both experiments is a force-extension relation. We use a one-dimensional model to show that in general the two quantities are not equal.
Bustamante C +9 more
core +1 more source