Results 51 to 60 of about 1,002,447 (253)

When ‘the Use of Force’ is Prohibited? – Article 2 (4) and the ‘Threshold’ of the Use of Force

open access: yesPrzegląd Prawniczy Uniwersytetu im. Adama Mickiewicza, 2018
This article advances the thesis that there is no threshold of the use of force. i.e. no level of the use of force which decides whether and which forcible actions undertaken by States are prohibited. The examples of actions discussed in the doctrine of
Agata Kleczkowska
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Unilateral Enforcement of Un Security Council Resolutions: The Case of Operation Iraqi Freedom

open access: yesJournal of Legal Studies, 2018
The prohibition of armed aggression under Article 2(2) of the United Nations Charter is one of the most important developments in international law and international relations in the modern era.
Ansong Alex
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

How Does it End Well?An Interview Study of Police Officersʼ Perceptions of De-escalation

open access: yesNordic Journal of Studies in Policing
Conflict de-escalation in police-citizen encounters is an under-researched topic despite increased focus from the public and the media. This paper aims to increase the understanding of how police officers attempt to de-escalate conflict through detailed ...
Hans Myhre Sunde
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Peace treaties in the 21st century: Treaty validity at the crossroads of the principle of peaceful settlement of disputes and the prohibition of the use of force [PDF]

open access: yesPravni Zapisi
Peace treaties remain the central instruments of war termination, yet their legal nature is under-theorized in light of the UN Charter's prohibition of the use of force and the duty of peaceful settlement.
Szalai Anikó
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The Use of Force against International Terrorrism: Everithing Changes, Nothing Remains Still

open access: yesPaix et Sécurité Internationales, 2018
This article analyses the legality of international society’s reactions to terrorism with the use of force. It considers, in particular, the cases where States have interpreted the use of force prohibition and the right to self-defence extensively and ...
Maria Jose Cervell Hortal
doaj   +1 more source

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