Results 51 to 60 of about 2,999,855 (295)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Gades and the Mediterranean: a Process of Integration [PDF]

open access: yes, 2019
The impetus for this paper is to present possible contributions of the Network Theory approach to the analysis of the Roman presence in Turdetania by the end of the 1st millennium BC.
dos Santos Silva, Bruno
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Deficits in executive functions but not in decision making under risk in individuals with problematic social-network use

open access: yesComprehensive Psychiatry, 2021
Background: The tendency to strive for immediate gratification by neglecting potential negative long-term outcomes characterizes addictive behaviors, such as substance use or gaming disorder.
Silke M. Müller   +5 more
doaj   +1 more source

Culture or social interaction? A study of influential factors on weblog design [PDF]

open access: yes, 2010
The importance of blogs and social networking as medium of interactions had gain substantial popularity in mainstream media. Such popularity is due to blogs timely publication, ease of use and wide availability.
Ali, M, Lee, H
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Using the Think-Aloud Method to Assess the Feasibility and Acceptability of Network Canvas Among Black Men Who Have Sex With Men and Transgender Persons: Qualitative Analysis

open access: yesJMIR Formative Research, 2021
BackgroundCharacteristics of an individual’s social network have been important factors in understanding infectious disease transmission patterns.
Natalie D Crawford   +6 more
doaj   +1 more source

Coauthorship and Thematic Networks in AAEP Annual Meetings

open access: yes, 2015
We analyze the coauthorship production of the AAEP Annual Meeting since 1964. We use social network analysis for creating coauthorship networks and given that any paper must be tagged with two JEL codes, we use this information for also structuring a ...
Larrosa, Juan M. C.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Veri Madenciliği Teknikleri Kullanılarak Ortaokul Öğrencilerinin Sosyal Ağ Kullanım Analizi: Kocaeli İli Örneği

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2015
Günümüzde sosyal ağ kullanımı oldukça artmıştır. Bu çalışmada Kocaeli İlinde yer alan Ulusal Egemenlik Ortaokulu öğrencileri üzerinde anket uygulaması gerçekleştirilmiş, toplanan anket sonuçları veri madenciliği teknikleri kullanılarak analiz edilmiştir.
Meltem Kurt Pehlivanoğlu, Nevcihan Duru
doaj  

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