Results 71 to 80 of about 2,999,855 (295)

Network modeling of problematic social media use components in college student social media users

Frontiers in Psychiatry
BackgroundWhile the constitutive features of problematic social media use (PSMU) have been formulated, there has been a lack of studies in the field examining the structure of relationships among PSMU components.MethodThis study employed network analytic
Jianyong Chen, Jianyong Chen, Ting Su, Ting Su, Junqiang Dong, Yuzhi Li, Yuzhi Li, Ju Feng, Ju Feng, Yingxiu Chen, Yingxiu Chen, Gu Liu, Gu Liu   +12 more
doaj   +1 more source

Networks and Our Limited Information Horizon

, 2006
In this paper we quantify our limited information horizon, by measuring the information necessary to locate specific nodes in a network. To investigate different ways to overcome this horizon, and the interplay between communication and topology in ...
Bilke S., Erdős P., Jeffrey T., K. SNEPPEN, Kochen M., M. ROSVALL, Milgram S.   +6 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Use of an Online Social Network to Introduce and Connect Newly Admitted International Students

JANZSSA, 2011
This article is a review of what East Carolina University’s (ECU) Office of International Affairs (OIA) carries out in regards to assisting new international students transitioning to the institution, prior to their arrival on campus.
William Mallett
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

“USE OF SOCIAL NETWORK ANALYSIS AS A STRATEGY FOR E-COMMERCE RECOMMENDATIONS”

Simetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2019
Agen Recommender sedang banyak digunakan oleh bisnis E-commerce untuk membantu pelanggan mengambil keputusan dari sejumlah besar pilihan. Untuk meningkatkan kinerja agen rekomendasi, tiga pendekatan utama (pendekatan berbasis konten, pendekatan ...
Daniel Adi Setya Rahardjo
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Exponential-family Random Network Models

, 2012
Random graphs, where the connections between nodes are considered random variables, have wide applicability in the social sciences. Exponential-family Random Graph Models (ERGM) have shown themselves to be a useful class of models for representing com ...
Fellows, Ian, Handcock, Mark S.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source