Results 41 to 50 of about 4,089,439 (298)

Survey of Canadian animal-based researchers' views on the Three Rs: replacement, reduction and refinement. [PDF]

open access: yesPLoS ONE, 2011
The 'Three Rs' tenet (replacement, reduction, refinement) is a widely accepted cornerstone of Canadian and international policies on animal-based science.
Nicole Fenwick   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

UK spotlight on alternatives to using animals [PDF]

open access: yesNature, 1999
london The British government has promised to carry out an audit of government-funded research into alternatives to the use of animals in research.
openaire   +2 more sources

Using Animation in Diagrammatic Theorem Proving [PDF]

open access: yes, 2002
Diagrams have many uses in mathematics, one of the most ambitious of which is as a form of proof. The domain we consider is real analysis, where quantification issues are subtle but crucial. Computers offer new possibilities in diagrammatic reasoning, one of which is animation. Here we develop animated rules as a solution to problems of quantification.
Bundy, Alan   +3 more
openaire   +2 more sources

Dominance in domestic dogs revisited: Useful habit and useful Construct? [PDF]

open access: yes, 2014
In the last decade, the validity and relevance of the dominance model was regularly put into question regarding relationships between canids like dogs and wolves, and consequently, humanedog relationships as well.
Vinke, C.M.   +6 more
core   +1 more source

Inalienable rights and pluralism in animal advocacy

open access: yesAnimal Sentience, 2016
I comment on two of Ng’s suggestions. There is a lack of support for his suggestion that some experiments on individual animals will be useful for future success, so they should be permitted. I also question his recommendation that animal advocacy should
Beril Sözmen
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Acknowledgement to Reviewers of Animals in 2014

open access: yes, 2015
The editors of Animals would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2014:[...
Animals Office, Animals Editorial Office
core   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Prevalence of Prostate Cancer Metastases after Intravenous Inoculation Provides Clues into the Molecular Basis of Dormancy in the Bone Marrow Microenvironment

open access: yesNeoplasia: An International Journal for Oncology Research, 2012
Bone is the preferred metastasis site of advanced prostate cancer (PCa). Using an in vivo murine model of human PCa cell metastasis to bone, we noted that the majority of animals that develop skeletal metastasis have either spinal lesions or lesions in ...
Younghun Jung   +16 more
doaj   +1 more source

Home - About - Disclaimer - Privacy