Results 81 to 90 of about 463,209 (335)

D2.1. User Centered Design

open access: yes, 2019
D2.1 documents all activities and their results in the development of ImAC user scenarios and provides detailed user cases for the selected ...
MATAMALA, ANNA, ORERO, PILAR
openaire   +2 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Human/User Centered Design

open access: yes, 2023
“User Centered Design” e “Human Centered Design” sono due locuzioni usate talvolta come sinonimi ma erroneamente in quanto sottendono significati diversi. Si tratta di due approcci al progetto e alla risoluzione dei problemi basati sullo spostamento del baricentro di attenzione dal prodotto/processo da progettare all’utente finale e alle sue esigenze ...
openaire   +2 more sources

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

An Approach to Decompose and Evaluate a Complex GIS-Application Design to a Simple, Lightweight, User-Centered App-Based Design Using User Experience Evaluation

open access: yesISPRS International Journal of Geo-Information, 2020
Working with contemporary, monolithic desktop Geographical Information Systems can be laborious and confusing, especially for non-experts. An alternative for a more user friendly approach to spatial data edition and spatial analysis may be an “app-based”
David Kammerhofer, Johannes Scholz
doaj   +1 more source

Improving situation awareness of a single human operator interacting with multiple unmanned vehicles: first results [PDF]

open access: yes, 2010
In the context of the supervision of one or several unmanned vehicles by a human operator, the design of an adapted user interface is a major challenge.
Aubert, Thomas   +5 more
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

User-Centered Evaluation of Adaptive and Adaptable Systems [PDF]

open access: yes, 2009
Adaptive and adaptable systems provide tailored output to various users in various contexts. While adaptive systems base their output on implicit inferences, adaptable systems use explicitly provided information. Since the presentation or output of these
Geest, Thea M. van der   +2 more
core   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Rancang Bangun Aplikasi Bimbingan Skripsi Menggunakan Metode User Centered Design (Ucd) [PDF]

open access: yes, 2019
Bidang pendidikan khususnya Universitas, pada saat ini membutuhkan dukungan sistem informasi dalam peningkatan mutu pelayanan terhadap proses pendidikan. Proses pendidikan ini sangat banyak jenisnya diantaranya adalah bimbingan tugas akhir.
Apridiansyah, Y. (Yovi)   +1 more
core   +1 more source

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