Results 41 to 50 of about 876,774 (280)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

MultiMice Air Hockey. A Game with a Low-Cost Non-Conventional Interface

open access: yesJournal of Computer Science and Technology, 2010
Interaction between user and computer is gradually going beyond the traditional mouse and keyboard. New ways of interaction are emerging, which use new and different means for data acquisition.
Damián Flores Choque   +2 more
doaj  

NUI framework based on real-time head pose estimation and hand gesture recognition

open access: yesMATEC Web of Conferences, 2016
The natural user interface (NUI) is used for the natural motion interface without using device or tool such as mice, keyboards, pens and markers. In this paper, we develop natural user interface framework based on two recognition module.
Kim Hyunduk   +2 more
doaj   +1 more source

Quantum Computer Emulator [PDF]

open access: yes, 1999
We describe a quantum computer emulator for a generic, general purpose quantum computer. This emulator consists of a simulator of the physical realization of the quantum computer and a graphical user interface to program and control the simulator.
De Raedt, Hans   +3 more
core   +7 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Software development system for creation adaptive user interfaces

open access: yesНаучно-технический вестник информационных технологий, механики и оптики
To improve the efficiency of the design engineer, the use of design automation systems is required. Currently, computer-aided design tools are multifunctional and have an expanded user interface.
L. F. Tagirova   +2 more
doaj   +1 more source

After the editing is done: Designing a Graphic User Interface for digital editions

open access: yesDigital Medievalist, 2012
With its origins dating back only to the second half of the twentieth century, Computer Science can be considered a very young discipline. The widespread adoption of the "Personal Computer" is even more recent. Introduced in the 1970s, its ascendancy was
Roberto Rosselli Del Turco
doaj   +1 more source

KBS Development [PDF]

open access: yes, 1991
The Knowledge Based System (KBS) has two main objectives, the provision of easy access to all the industrial and scientific codes through an executive program, and the provision of an easy to use user interface for the analysis codes.
Aggarwal, Bharat
core   +1 more source

A grammatical specification of human-computer dialogue [PDF]

open access: yes, 1995
The Seeheim Model of human-computer interaction partitions an interactive application into a user-interface, a dialogue controller and the application itself.
Nymeyer, Albert
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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