Results 51 to 60 of about 5,479,777 (297)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Flexible physical interfaces [PDF]

open access: yes, 2007
Human-computer interface devices are rigid, and afford little or no opportunity for end-user adaptation. This thesis proposes that valuable new interaction possibilities can be generated through the development of user interface hardware that is ...
Villar, Nicolas
core   +4 more sources

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

User Interface Aspects of a Human-Hand Simulation System [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2005
This paper describes the user interface design for a human-hand simulation system, a virtual environment that produces ground truth data (life-like human hand gestures and animations) and provides visualization support for experiments on computer vision ...
Beifang Yi   +3 more
doaj  

After the editing is done: Designing a Graphic User Interface for digital editions

open access: yesDigital Medievalist, 2012
With its origins dating back only to the second half of the twentieth century, Computer Science can be considered a very young discipline. The widespread adoption of the "Personal Computer" is even more recent. Introduced in the 1970s, its ascendancy was
Roberto Rosselli Del Turco
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Research on Optimal Design of Visual Elements of CNC Press Display Interface Based on Visual Cognition

open access: yesApplied System Innovation
With the rapid development of artificial intelligence and computer technology, digital interfaces have become central to CNC press operations. However, effectively presenting complex information within limited display space while reducing cognitive load ...
Hao Yuan, Yiting Wang, Jiawei Zhong
doaj   +1 more source

An Adaptive Brain Actuated System for Augmenting Rehabilitation

open access: yesFrontiers in Neuroscience, 2014
For people living with paralysis, restoration of hand function remains the top priority because it leads to independence and improvement in quality of life.
Scott Alan Roset   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Database Graphic User Interface correspondence with Ellis Information Seeking behavior Model

open access: yesIranian Journal of Information Processing & Management, 2010
Graphic User interface serves as a bridge between man and databases. Its primary purpose is to assist uses by establishing interaction with computer systems.
Muhammad Azami, Rahmatullah Fatahi
doaj  

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