Results 91 to 100 of about 1,150,410 (270)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Facilitating User Driven Innovation – A Study of Methods and Tools at Herlev Hospital [PDF]
, 2011 Purpose: To present the preliminary research results of user driven innovation methods at healthcare facilities and their relevance to research and practice. Background/Approach: The paper is based on a case study conducted at the Gynaecologic Department
Fronczek-Munter, Aneta
core +1 more source
Information Systems and Health Care X: A User-Driven Approach to Personal Health Records
Communications of the Association for Information Systems, 2006 User acceptance issues and user-centered design have long been an important theme in information systems research. In the field of health care information systems, much attention has been devoted to user issues in the health care provider domain, e.g. physicians, nurses, medical records.
Deborah Beranek Lafky +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Speech Driven Environmental Control System (SPECS) From Specification to Prototype [PDF]
The SPECS project is designing a new speech driven environmental control to include use by people with dysathric speech. The project is funded by the National Institute for Health Research and is developing the device with a large UK assistive technology
Judge, Simon, Robertson, Zoe
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Informacijos Mokslai, 2013 Šio mokslinio tyrimo tematika nagrinėja internetinių paslaugų kompozicijos atlikimo priemones ir būdus. Straipsnyje aprašomi vartotojo poreikiams pritaikytų internetinių paslaugų kompozicijos automatiniai ir pusiau automatiniai kūrimo būdai ir metodai ...
Dalė Dzemydienė, Arūnas Miliauskas
doaj +1 more source
Automated control of hierarchical systems using value-driven methods [PDF]
An introduction is given to the Value-driven methodology, which has been successfully applied to solve a variety of difficult decision, control, and optimization problems.
Burke, Thomas E., Pugh, George E.
core +1 more source
A multi-driven approach to requirements analysis of data warehouse model: A case study [PDF]
, 2013 In this paper, a multi-driven approach to data modeling in data warehousing will be presented, which integrates three existing approaches normally used separately: goal-driven, user-driven and data-driven; and two approaches usually not used in data ...
Carvalho, João Álvaro +2 more
core
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source