Results 71 to 80 of about 1,312,492 (269)

Co-design: from expert- to user-driven ideas in public service design

Public Management Review, 2019
While co-design with users has evolved as a promising approach to service innovation, it remains unclear how it can be used in public service contexts. This article addresses this knowledge gap by applying a co-design framework during the ideation stage ...
Jakob Trischler, Timo Dietrich, S. Rundle-Thiele   +2 more
semanticscholar   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

K-Means Clustering and Linear Regression for User Phase Identification, Verification, and Topology Determination Under Varied Smart Meter Penetration

Energies
Rapid evolution of electricity distribution networks challenges the maintenance of up-to-date information in electricity utility databases. This hinders the ability of utilities to understand phase connectivity and topology of users in their distribution
Tharushi Kalinga, Brendan Banfield, Jonathan C. Knott, Duane A. Robinson   +3 more
doaj   +1 more source

Activity Monitoring Process based on Model-Driven Engineering – Application to Ambient Assisted Living

Journal of Intelligent Systems, 2015
The supervisor of the activities of a system user should benefit from the knowledge contained in the event logs of the user. They allow the monitoring of the sequential and parallel user activities.
Simonin Jacques, Soulas Julie, Lenca Philippe   +2 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

A New Approach towards a User-Driven Coastal Climate Service to Enhance Climate Resilience in European Cities

Sustainability, 2023
Coastal climate services play a crucial role in developing customised climate information for diverse end-users and stakeholders. To build climate-resilient societies, decision-makers should be empowered through easy access to powerful tools that enable timely adaptation to future and ongoing hazards.
Roberta Paranunzio, Iulia Anton, Elisa Adirosi, Tasneem Ahmed, Luca Baldini, Carlo Brandini, Filippo Giannetti, Cécil Meulenberg, Alberto Ortolani, Francesco Pilla, Gregorio Iglesias, Salem Gharbia   +11 more
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Model-driven web engineering methods: a literature review

Revista Facultad de Ingeniería Universidad de Antioquia, 2012
This paper presents some of the model-driven Web engineering methods that have been proposed, and discusses and analyzes the advantages and disadvantages of such methods regarding current tendencies and best practices on model-driven engineering.
Jesús Andrés Hincapié Londoño, Jhon Freddy Duitama   +1 more
doaj   +1 more source