Results 61 to 70 of about 5,626,798 (290)
Sensory semantic user interfaces (SenSUI) [PDF]
, 2009 Rapid evolution of the World Wide Web with its underlying sources of data, knowledge, services and applications continually attempts to support a variety of users, with different backgrounds, requirements and capabilities.
Bell, D, Heravi, BR, Lycett, M
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Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
User interface development and software environments : the Chiron-1 system [PDF]
, 1990 User interface development systems for software environments have to cope with the broad, extensible and dynamic character of such environments, must support internal and external integration, and should enable various software development strategies ...
Cameron, Mary +3 more
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Embodied User Interfaces: Towards Invisible User Interfaces [PDF]
, 1999 There have been several recent examples of user interface techniques in which the user uses a computational device by physically manipulating the device. This paper proposes that these form an interesting new paradigm for user interface design, Embodied User Interfaces.
Beverly L. Harrison +2 more
openaire +2 more sources
The R Commander: A Basic-Statistics Graphical User Interface to R
, 2005 Unlike S-PLUS, R does not incorporate a statistical graphical user interface (GUI), but it does include tools for building GUIs. Based on the tcltk package (which furnishes an interface to the Tcl/Tk GUI toolkit), the Rcmdr package provides a basic ...
J. Fox
semanticscholar +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Beautiful interfaces. From user experience to user interface design [PDF]
The Design Journal, 2017 The paper is aimed to explore and to conduct a critical review of the latest position in the debate of the aesthetic dimension of visual design applied to graphical, multimodal and virtual interfac...
openaire +4 more sources
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
SGSDesigner, the ODESGS Environment User Interface
, 2006 In this demo, we will show SGSDesigner, the ODESGS Environment user interface. ODESGS Environment (the realization of the ODESGS Framework [1]) is an environment for supporting both a) the annotation of pre-existing Grid Services(GSs) and b) the design
González-Cabero, R., Gómez-Pérez, A.
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