Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
William Gibson's Neuro-Metaphor of User Interface
The authors actualize the problem of studying neuro-metaphor as an element of the user interface human-computer. By analyzing the epistemological boundaries of the concepts information and interface in theoretical discussions of the philosophy of science
Gennady V. Bakumenko+2 more
doaj +1 more source
Embodied User Interfaces: Towards Invisible User Interfaces [PDF]
There have been several recent examples of user interface techniques in which the user uses a computational device by physically manipulating the device. This paper proposes that these form an interesting new paradigm for user interface design, Embodied User Interfaces.
Beverly L. Harrison+2 more
openaire +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Beautiful interfaces. From user experience to user interface design [PDF]
The paper is aimed to explore and to conduct a critical review of the latest position in the debate of the aesthetic dimension of visual design applied to graphical, multimodal and virtual interfac...
openaire +4 more sources
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Database Graphic User Interface correspondence with Ellis Information Seeking behavior Model
Graphic User interface serves as a bridge between man and databases. Its primary purpose is to assist uses by establishing interaction with computer systems.
Muhammad Azami, Rahmatullah Fatahi
doaj
Usability Analysis of the IBOSS PTSP BP Batam User Interface Using Heuristic Evaluation
This research investigates user dissatisfaction with the IBOSS user interface, reported by 54% of users in an initial survey, and aims to improve the interface through heuristic evaluation and subsequent redesign using Gestalt principles.
Bintang Febrian Alamandha, Rina Yulius
doaj +1 more source
The Role of Tangible Interfaces in Enhancing Children's Engagement in Learning
This paper presents the results of an exploratory study in which the authors investigated the impact of tangible interface used by children at the elementary school level.
Rante Hestiasari+2 more
doaj +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source