Results 61 to 70 of about 33,870 (219)

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

Mutational screening of the USH2A gene in Spanish USH patients reveals 23 novel pathogenic mutations

open access: yesOrphanet Journal of Rare Diseases, 2011
Background Usher Syndrome type II (USH2) is an autosomal recessive disorder, characterized by moderate to severe hearing impairment and retinitis pigmentosa (RP).
Diaz-Llopis Manuel   +13 more
doaj   +1 more source

Living with Usher Syndrome: Patient and Physician Perspectives

open access: yesOphthalmology and Therapy, 2020
Plain Language Summary In this patient–physician perspective a patient with Usher syndrome shares her experience. Usher syndrome affects both hearing and vision.
Helene Lønborg-Møller   +2 more
doaj   +1 more source

Novel grading system for quantification of cystic macular lesions in Usher syndrome [PDF]

open access: yes, 2015
International audienceBackground: To evaluate novel grading system used to quantify optical coherence tomography (OCT) scans for cystic macular lesions (CML) in Usher syndrome (USH) patients, focusing on CML associated alterations in MOY7A and USH2A ...
Mohand-Said, Saddek   +3 more
core   +4 more sources

The dynamics of cyclic‐periodic phenomena during non‐rapid and rapid eye movement sleep

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep is a complex physiological state characterized by distinct stages, each exhibiting unique electroencephalographic patterns and physiological phenomena. Sleep research has unveiled the presence of intricate cyclic‐periodic phenomena during both non‐rapid eye movement and rapid eye movement sleep stages. These phenomena encompass a spectrum
Maria P. Mogavero   +5 more
wiley   +1 more source

Loss of Foveal Cone Structure Precedes Loss of Visual Acuity in Patients With Rod-Cone Degeneration. [PDF]

open access: yes, 2019
PurposeTo assess the relationship between cone spacing and visual acuity in eyes with rod-cone degeneration (RCD) followed longitudinally.MethodsHigh-resolution images of the retina were obtained using adaptive optics scanning laser ophthalmoscopy from ...
Bensinger, Ethan   +9 more
core  

In vivo genetic manipulation of inner ear connexin expression by bovine adeno-Associated viral vectors [PDF]

open access: yes, 2017
We have previously shown that in vitro transduction with bovine adeno-associated viral (BAAV) vectors restores connexin expression and rescues gap junction coupling in cochlear organotypic cultures from connexin-deficient mice that are models DFNB1 ...
Campioni, Matteo   +7 more
core   +1 more source

Periods, Pains, Pills, and Performance—Fighting Blood, Bodies and Biology

open access: yesSociological Forum, EarlyView.
ABSTRACT This paper draws on various data from long‐term immersion in combat sports to explore the period experiences of cis women fighters. We blend theoretical ideas from the social scientific literature on menstruation and the sociology of medicalization, pain and injury.
Reem AlHashmi   +2 more
wiley   +1 more source

Microtubule motors transport phagosomes in the RPE, and lack of KLC1 leads to AMD-like pathogenesis. [PDF]

open access: yes, 2015
The degradation of phagosomes, derived from the ingestion of photoreceptor outer segment (POS) disk membranes, is a major role of the retinal pigment epithelium (RPE). Here, POS phagosomes were observed to associate with myosin-7a, and then kinesin-1, as
Diemer, Tanja   +6 more
core   +1 more source

Impact of template backbone heterogeneity on RNA polymerase II transcription. [PDF]

open access: yes, 2014
Variations in the sugar component (ribose or deoxyribose) and the nature of the phosphodiester linkage (3'-5' or 2'-5' orientation) have been a challenge for genetic information transfer from the very beginning of evolution.
Chong, Jenny   +5 more
core   +1 more source

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