Demographic features and prognostic factors of uterine carcinosarcoma: a study at a specialized center in Saudi Arabia [PDF]
ObjectivesUterine carcinosarcoma is a rare, aggressive biphasic tumor comprising both carcinomatous and sarcomatous elements. The overall prognosis of women with uterine carcinosarcoma is poor, with a median overall survival of less than two years.
Wala Mehros +17 more
doaj +2 more sources
A rare case report of uterine carcinosarcoma with bilateral ovarian Brenner tumors [PDF]
BackgroundUterine carcinosarcoma is a rare, highly aggressive malignancy characterized by both carcinomatous and sarcomatous components. Brenner tumors of the ovary are uncommon epithelial neoplasms, usually benign but occasionally coexisting with other ...
Xinyao Wan +3 more
doaj +2 more sources
The discovery of uterine carcinosarcoma through a sister mary joseph's nodule: A case report [PDF]
The Sister Mary Joseph nodule is a rare sign of advanced malignancy, including uterine carcinosarcoma. A 55-year-old woman presented with a necrotic, bleeding 4 cm umbilical mass.
Wissal Jaafar +5 more
doaj +2 more sources
Complete response to trastuzumab-deruxtecan (Enhertu, T-DXd) in HER2-positive stage IVB uterine carcinosarcoma [PDF]
Objectives: To report a case of complete response to trastuzumab-deruxtecan (T-DXd) in a patient with HER2-positive stage IVB uterine carcinosarcoma, and to contextualize this within evolving therapy for HER2-positive gynecologic malignancies.
Michael Kim +4 more
doaj +2 more sources
Peritoneal cytology predicting distant metastasis in uterine carcinosarcoma: machine learning model development and validation [PDF]
Objective This study develops and validates a machine learning model using peritoneal cytology to predict distant metastasis in uterine carcinosarcoma, aiding clinical decision-making.
Qiaoming Lin +4 more
doaj +2 more sources
Case report: Characterization of the immunologic and molecular landscape in a unique presentation of invasive lobular carcinoma with concurrent uterine carcinosarcoma treated with immunotherapy [PDF]
Invasive lobular breast cancer (ILC) is characterized by a relatively high risk for late recurrence and a unique metastatic pattern with an increased risk for metastasis to gynecologic organs and peritoneum. We present a unique case of recurrent ILC with
Courtney J. Riedinger +5 more
doaj +2 more sources
Elucidating divergent biology in uterine carcinosarcoma [PDF]
Objectives: Uterine carcinosarcoma (UCS) is an aggressive malignancy characterized by epithelial (C) and mesenchymal (S) components, with complex biology and poor treatment response.
Vikas Garg +18 more
doaj +2 more sources
Prognostic Significance of the Ki-67 Index with an Optimal Cut-off Value of 32.5% in Uterine Sarcoma and Uterine Carcinosarcoma: A Retrospective Cohort Study [PDF]
Piaopiao Ye,1 Fang Wang,2 Xinyue Dai,1 Xiaoli Hu,1 Yuanqiu Wang11Department of Obstetrics and Gynecology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2Department of Pathology, The First ...
Ye P, Wang F, Dai X, Hu X, Wang Y
doaj +2 more sources
Uterine carcinosarcoma, which is categorized as high-grade endometrial cancer, is an uncommon kind of malignant gynecological neoplasms. Clinically, this tumor frequently affects menopausal women and the main symptom is abnormally postmenopausal vaginal ...
Ho Xuan Tuan, MD, PhD +4 more
doaj +1 more source
cERBB-2/Her-2 Neu Overexpression and Prognostic Significance in Uterine Carcinosarcoma
Objective: There is not enough data in the literature regarding Her-2 overexpression in uterine carcinosarcomas or its association with the prognosis. The aim of this study was to determine the Her-2 overexpression rate in uterine carcinosarcoma and to ...
Huseyin Salih SEMIZ +5 more
doaj +1 more source

