Results 71 to 80 of about 118,119 (154)
We report a novel cysteine‐to‐serine surface‐mutation approach to determine co‐crystal structures of KAT6A with small‐molecule inhibitors and compare it with the previously published MYSTcryst approach which uses mutated KAT8 as a surrogate for KAT6A.
Vera Puetter +8 more
wiley +1 more source
A 71-year-old woman with suspected endometrial cancer underwent robotic-assisted hysterectomy, bilateral salpingo-oophorectomy, pelvic and para-aortic lymph node dissection, and infracolic omentectomy revealing a stage II uterine carcinosarcoma with ...
Monica Dandapani +3 more
doaj +1 more source
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley +1 more source
Disappearing Uterine Carcinosarcoma Following Uterine Artery Embolisation
Aims To report the resolution of uterine carcinosarcoma in a patient who presented with profuse vaginal bleeding requiring uterine artery embolisation (UAE) to control bleeding.
Choi, KMC +5 more
core
Malignant mixed Mullerian tumor: A rare case report
Malignant mixed Mullerian tumor of the uterus, also called carcinosarcoma, is a very rare and aggressive type of malignancy with epithelial and mesenchymal components. Therefore, it is considered a metaplastic carcinoma.
Prasmit Amit Shah +4 more
doaj +1 more source
Carcinosarcoma of the uterus is a rare tumor representing 2-4% of uterine malignancies. Its prognosis is poor with a 5 years survival rate of 10-30%. We report a first documented case of carcinosarcoma occurring in a 62 years old woman who presented with
Zacharie Sando +5 more
doaj +1 more source
Uterine carcinosarcoma associated with pelvic radiotherapy for sacral chordoma: A case report
Objective: Postirradiation sarcoma of the female genital tract is rare, but a recognized event. Most reported cases have been associated with history of radiotherapy for various gynecologic conditions, particularly cancer of the uterine cervix and ...
Korhan Kahraman +3 more
doaj +1 more source
BackgroundUterine carcinosarcoma is a rare and highly aggressive gynecologic malignancy with a poor prognosis after recurrence. Superior vena cava syndrome (SVCS) caused by mediastinal recurrence of uterine carcinosarcoma is exceedingly rare, and its ...
Naóe Kinoshita +10 more
core +1 more source
Genetic Investigation of Uterine Carcinosarcoma: Case Report and Cohort Analysis
Background Uterine carcinosarcoma, a rare gynecological malignancy, often presents at the advanced stage with a poor prognosis because current therapies have not improved rates of survival.
Timothy N. Hembree +3 more
core +1 more source
Metastasis of Colon Cancer to the Accessory Spleen: A Case Report
Distant metastasis to the spleen is extremely rare. To the best of our knowledge, metastasis to the accessory spleen based on pathological findings has only been reported in four patients in the English literature, including one each of ovarian cancer,
Sohyun Park +5 more
doaj +1 more source

