Results 51 to 60 of about 118,119 (154)

Durable complete remission with aromatase inhibitor therapy in a patient with metastatic uterine carcinosarcoma with poor performance status and coagulation disorders: a case report

Journal of Medical Case Reports, 2017
Background Chemotherapy is considered the most appropriate treatment for metastatic uterine sarcoma, despite its limited efficacy. No other treatment has been conclusively proved to be a real alternative, but some reports suggest that anti-hormonal ...
P. Martin-Romano, M. Jurado, M. A. Idoate, L. Arbea, J. L. Hernandez-Lizoain, D. Cano, J. A. Paramo, S. Martin-Algarra   +7 more
doaj   +1 more source

Carcinosarcoma of Uterus with Left Adnexal Metastasis: A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2019
Carcinosarcomas are rare and aggressive tumour consisting of both carcinomatous and sarcomatous elements within same tumour. These tumours are supposed to arise from monoclonal proliferation of epithelial component.
Ruchi Agarwal, Kulwant Singh, Monika Gathwal, Yudhvir Singh, Swarn Kaur   +4 more
doaj   +1 more source

HierAnom‐Path: Zero‐Shot Rare Cancer Detection in Histopathology via Hierarchical Foundation Model Adaptation

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Rare cancers collectively represent 20%–25% of all malignancies yet yield fewer than 50 annotated whole‐slide images (WSIs) per subtype in publicly available archives, rendering supervised deep learning inapplicable. We present HierAnom‐Path, to the best of our knowledge, the first framework for zero‐shot rare cancer anomaly detection in ...
Noora Saleem Jumaah, Mohanad Sameer Jabbar, Saif H. Alwaeli, Noor Ayesha, Mohamed Babiker A. Mohamed, Muhammad I. Khan   +5 more
wiley   +1 more source

Molecular Tumor Boards in Malignant Melanoma: Uncovering Challenges and Opportunities in a Bicenter Retrospective Analysis in Germany

International Journal of Cancer, Volume 159, Issue 9, Page 2290-2299, 1 November 2026.
Molecular tumor boards (MTB), interdisciplinary teams that use tumor genomic data to guide personalized treatment decisions, have emerged as a promising strategy in melanoma care, although their real‐world clinical impact remains uncertain. This retrospective study evaluated advanced melanoma patients to assess molecularly guided treatment ...
Glenn Geidel, Theresa Lowinus, Patrick Metzger, Rebecca Czurda, Vincent Schipperges, Ulrike Paul, Alessandra Rünger, Julian Kött, Isabel Heidrich, Saskia Lehr, Julia Kühn, Heiko Becker, Cornelius Miething, Martin Werner, Silke Laßmann, Justus Duyster, Tilman Brummer, Ronald Simon, Winfried Alsdorf, Maximilian Christopeit, Carsten Bokemeyer, Kilian Eyerich, Stefan W. Schneider, David Rafei, Melanie Börries, Frank Meiss, Christoffer Gebhardt   +26 more
wiley   +1 more source

Advanced Primary Cervical Carcinosarcoma With Ovarian and Peritoneal Metastases in a Premenopausal Woman: A Rare Case Report From Northern Tanzania

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Cervical carcinosarcoma (CCS), also known as malignant mixed Müllerian tumor (MMMT) of the cervix, is an exceptionally rare and aggressive biphasic neoplasm composed of both epithelial and mesenchymal malignant components. Due to its rarity, optimal management strategies are not well established, particularly in low‐resource settings.
John Lugata, Gidion Kategugwa, Kimberly R. Sladek, Abitalis Mayengela, Kenneth Bagandanshwa, Baraka Shao, Edrick Elias, Joseph Mlay, Bariki Mchome, Eusebious Maro, Alex Mremi, Fredrick Mbise   +11 more
wiley   +1 more source

Advances in the management of uterine fibroids [PDF]

, 2009
Uterine fibroids are extremely common, with major surgery the current main management option; uterine artery embolisation is an alternative, but risks to fertility are unclear.
Munro, Kirsty I, Critchley, Hilary Od
core   +1 more source

METTL3 Increases Temozolomide Resistance in MGMT‐Negative Glioblastoma by Enhancing CBX5 mRNA Stability in an m6A‐IGF2BP2‐Dependent Manner

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
METTL3‐dependent m6A modification and IGF2BP2‐associated CBX5 mRNA stabilization help maintain CBX5 expression in MGMT‐negative glioblastoma. During temozolomide (TMZ) treatment, CBX5 contributes to ATM–RAD51‐associated signaling, limits persistent DNA damage and apoptosis, and thereby supports cell survival and TMZ resistance.
Hui Deng, Ruoyu Chen, Daohong Qu, Cifu Qu, Jia Shi   +4 more
wiley   +1 more source

Carcinosarcoma of the Uterine Corpus with Alpha-Fetoprotein-Producing Hepatoid Adenocarcinoma: A Report of Two Cases

Case Reports in Oncology, 2011
We report two cases of uterine carcinosarcoma associated with alpha-fetoprotein (AFP)-producing hepatoid adenocarcinoma. Samples were obtained from two women aged 63 and 82 years.
Ryuji Kawaguchi, Naoto Furukawa, Yoshihiko Yamada, Hidekazu Ooi, Hiroshi Kobayashi   +4 more
doaj   +1 more source

Incidence of Gynecological Cancers Is Rising in Northern Iran: A Population‐Based, Serial Cross‐Sectional Joinpoint Regression Study

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Gynecological cancers are a major global health burden, with ovarian, uterine, and cervical cancers being the most common types. Despite rising national incidence rates, recent comprehensive data for Gilan Province remain limited.
Mohammad Amouzadeh‐Lichahi, Sahand Karimzadhagh, Nooshin Zaresharifi, Azadeh Jafari, Paridokht Karimian, Maryam Jafari, Gholamreza Sadeghi, Mohammad Ali Yazdanipour   +7 more
wiley   +1 more source

Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer

MedComm, Volume 7, Issue 10, October 2026.
Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta, Ramakrishna Vadde, Ganji Purnachandra Nagaraju   +2 more
wiley   +1 more source