Results 91 to 100 of about 42,572 (273)

Validation of data quality in the Swedish quality register of gynecologic cancer for cervical cancer and vulvar cancer—a Swedish gynecologic cancer group (Swe‐GCG) study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
The aim of this study was to evaluate the quality of data in the Swedish Quality Register of Gynecologic Cancer (SQRGC on cervical cancer and vulvar cancer in terms of completeness, timeliness, comparability, and validity according to the International Agency for Research on Cancer methodology.
Maria Bjurberg, Kristina Hellman, Tim A. Säll, Christian Staf, Christer Borgfeldt, Erik Holmberg, Jenny Jönsson, Gabriel Lindahl, Angelique Flöter Rådestad, Camilla Sköld, Katja Stenström Bohlin, Karin Stålberg, Elisabeth Åvall‐Lundqvist, Preben Kjølhede, Pernilla Dahm‐Kähler   +14 more
wiley   +1 more source

Efficacy and safety of laparoscopic lateral suspension with mesh for pelvic organ prolapse: A systematic review and meta‐analysis

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Laparoscopic lateral suspension (LLS) with mesh provides effective apical and anterior vaginal support for pelvic organ prolapse, with anatomical success rates exceeding 90% and a low complication profile. This meta‐analysis reinforces LLS as a reliable surgical option, though longer follow‐up is needed to confirm its long‐term efficacy.
Qi Wang, Stefano Manodoro, Xiaoxiang Jiang, Chaoqin Lin   +3 more
wiley   +1 more source

Vascular endothelial growth factor exression in uterine cervical cancer: correlation with clinicopathologic characteristics and survival [PDF]

, 2009
Aim: This retrospective study was performed to determine the vascular endothelial growth factor (VEGF) expression in cervical cancer cells, and to examine its correlation with clinicopathologic characteristics and survival of patients.
Chekhun, V.F., Goncharuk, I.V., Lukyanova, N.Yu., Vorobjova, L.I.   +3 more
core  

Uterine volume assay after gonadotoxic therapies in childhood, adolescence, and young adulthood: A systematic review and Bayesian network meta‐analysis

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Recent studies have suggested the potential impact of high doses of chemotherapy on uterine volume, but this meta‐analysis did not find any significant decrease in uterine volume after chemotherapy. Abstract Introduction Uterine damage after pelvic radiotherapy or total‐body irradiation is well described, with decreased uterine volume and high ...
Eloïse Fraison, Stephanie Huberlant, Mathilde Cavalieri, Aurore Gueniffey, Justine Riss, Christine Rousset‐Jablonski, Blandine Courbiere   +6 more
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Cancer mortality in Europe, 2000-2004, and an overview of trends since 1975 [PDF]

, 2017
Background: To update the pattern of cancer mortality in Europe. Materials and methods: We analysed cancer mortality in 34 European countries during 2000-2004, with an overview of trends in 1975-2004 using data from the World Health Organization. Results:
Bertuccio, P., Bosetti, C., Boyle, P., La Vecchia, C., Levi, F., Lucchini, F., Negri, E.   +6 more
core  

Real‐World Data Analysis of Genomic Alterations Detected by a Dual DNA–RNA Comprehensive Genomic Profiling Test

Cancer Science, EarlyView.
This study analyzed 1356 cases using GenMineTOP, Japan's first dual DNA–RNA CGP test, and identified oncogenic alterations in 91.5% of cases. The RNA panel detected 105 fusion events, including 11 NTRK fusions. Furthermore, the analysis clarified the independent effects of genomic abnormalities and cancer type on RNA expression, providing valuable ...
Kousuke Watanabe, Miho Ogawa, Aya Shinozaki‐Ushiku, Shuichi Tsutsumi, Kenji Tatsuno, Hiroyuki Aburatani, Hidenori Kage, Katsutoshi Oda   +7 more
wiley   +1 more source

Polarity Gene PARD6B Promotes Tumor Growth of Colorectal Cancer via Increasing MYC Expression

Cancer Science, EarlyView.
Partitioning Defective 6B (PARD6B), a polarity gene, functions as a scaffold node for the Par protein complex. In this study, we showed that highly expressed PARD6B could promote CRC growth by upregulating MYC expression while suppressing miR‐34c expression.
Kosuke Hirose, Takaaki Masuda, Hajime Otsu, Taro Tobo, Kiyotaka Hosoda, Tadashi Abe, Yusuke Nakano, Masahiro Hashimoto, Takanari Tatsumi, Tomohiko Ikehara, Takashi Ofuchi, Shinsaku Itoyama, Yuki Ando, Yasuo Tsuda, Yusuke Yonemura, Keishi Sugimachi, Eiji Oki, Tomoharu Yoshizumi, Koshi Mimori   +18 more
wiley   +1 more source

Deep Phenotyping of Pathology‐Confirmed Benign Lesions in PTEN Hamartoma Tumor Syndrome Patients

Clinical Genetics, EarlyView.
Gastrointestinal, skin, thyroid, and vascular lesions are frequently present in PTEN Hamartoma Tumor Syndrome patients with little to no difference between sexes or by index status. Early‐onset lipomas (< 20 years) may be useful for early recognition of patients, and uterine polyps should be considered for inclusion as a PHTS‐related lesion.
Ane J. Schei‐Andersen, Janneke H. M. Schuurs‐Hoeijmakers, Rachel van der Post, Arjen R. Mensenkamp, Jolanda Schieving, PTEN Study Group, Muriel A. Adank, Mirjam de Jong, Marjolijn C.J. Jongemans, Liselotte P. van Hest, Yvette van Ierland, Edward M. Leter, Maartje Nielsen, Janet R. Vos, Nicoline Hoogerbrugge   +14 more
wiley   +1 more source

THER: Integrative Web Tool for Tumour Hypoxia Exploration and Research

Cell Proliferation, EarlyView.
THER: Integrative Web Tool for Tumor Hypoxia Exploration and Research.
Yasi Zhang, Huiying Liu, Pengpeng Zhang, BiCheng Ye, Haoxuan Ying, Hong Yang, Jian Zhang, Nan Zhang, Kailai Li, Ting Wei, Aimin Jiang, Anqi Lin, Peng Luo   +12 more
wiley   +1 more source