Results 131 to 140 of about 110,820 (315)

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

The Reserve Cell in the Uterine Cervix: aspects of development, differentiation and diagnosis [PDF]

, 2008
Carcinoma of the uterine cervix is worldwide the second most common cancer in women. It has been approximately 150 years since the first description of uterine cervical carcinoma, a century since the description of its precursor lesions, and half a ...
Muyden-Martens, J.E. (Jolise) van
core  

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Association Between Oral Lichen Planus and Non‐Oral Cancers: A Multicentre Case–Control SIPMO Study

Oral Diseases, EarlyView.
ABSTRACT Objectives This multicentre case–control study aimed to investigate the potential association between oral lichen planus (OLP) and extraoral cancers. The secondary objective included the identification of risk factors for this association. Methods The study was conducted between January 2023 and June 2024 and included 21 Italian Oral Medicine ...
Gioele Gioco, Anna Schiavelli, Alessandra Majorana, Elena Bardellini, Silvio Abati, Andrea Sardella, Francesco Spadari, Matteo Pellegrini, Dorina Lauritano, Raffaele Borgia, Monica Pentenero, Samuele Sutera, Paolo Giacomo Arduino, Alessio Gambino, Roberto Broccoletti, Matteo Biasotto, Giulia Ottaviani, Lorenzo Azzi, Alessandro D'Aiuto, Davide Bartolomeo Gissi, Andrea Gabusi, Andrea Santarelli, Marco Mascitti, Paolo Vescovi, Gloria Bortolotti, Maddalena Manfredi, Marco Meleti, Grazia Zino, Umberto Romeo, Gianluca Tenore, Gianfranco Favia, Luisa Limongelli, Massimo Petruzzi, Francesca Dimilito, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Giuseppina Campisi, Vera Panzarella, Stefania Leuci, Rosario Serpico, Alberta Lucchese, Giuseppe Colella, Giacomo Oteri, Antonia Marcianò, Gaetano Isola, Alessandro Polizzi, Amerigo Giudice, Elena Calabria, Umberto Mariani, Daniela Adamo, Federica Canfora, Filippo Graziani, Marco Nisi, Michele Giuliani, Luisa Ritrovato, Federica De Micheli, Cosimo Rupe, Francesco Scilla, Romeo Patini, Massimo Cordaro, Michele Davide Mignogna, Carlo Lajolo, SIPMO (Italian Society of Oral Pathology and Medicine)   +62 more
wiley   +1 more source

Clinical significance and immune microenvironment association of cuproptosis‐related genes in pan‐cancer

Experimental Physiology, EarlyView.
Abstract Recent studies highlight the important roles of cuproptosis in cancer cells. However, the roles of the cuproptosis‐related genes (CRGs) in different cancers are still not fully understood. Comprehensive analysis was performed using open‐source bioinformatic platforms to disclose the expression profiles, prognostic significance, genomic and ...
Xinyu Ge, Kaijing Wang, Tian Zhao, Jinyi Wang, Jie Liu, Zhengliang Sun, Zhengjun Chai, Wen Zhang, Chengbao Li, Yan Xu, Guohan Chen   +10 more
wiley   +1 more source

Caracterización de mujeres de Las Tunas con lesiones cérvico uterinas

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Fundamento: el cáncer cérvico uterino provoca anualmente la muerte de muchas mujeres a nivel mundial, la mayoría en los países en desarrollo.Objetivo: caracterizar a las pacientes estudiadas por lesiones cérvico uterinas, atendidas en el Hospital General
Rabiel Cárdenas Peña, Dianni Pérez Escalona, Ramón Jesús Cruz Pérez, Karen Luz Torres Rojas, Julio Antonio Pérez Pantoja   +4 more
doaj  

Uterine Perivascular Epithelioid Cell Tumour Presenting as a Cervical Mass [PDF]

, 2006
Perivascular Epithelioid Cell Tumour (PEComa) also known as myelomelanocytic tumours are uncommon, recently described mesenchymal tumours that include angiomyolipoma, clear cell sugar tumour of the lung, lymphangioleiomyoma and tumours composed ...
Azad, Najamul Sahar, Aziz, Aliya Begum, Kayani, Naila, Pervez, Shahid   +3 more
core   +1 more source

On why cancer cells require a great amount of glucose

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu, Aoran Liu, Rui Shi, Long Xu, Zhenyu Huang, Ye Zhang, Ying Xu   +6 more
wiley   +1 more source

When Endoscopic Sedation is Not an Option: Insights From a Multicenter on‐site Survey on Tolerance for Japanese Gastric Cancer Screening

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Esophagogastroduodenoscopy (EGD) is widely used for gastric cancer (GC) screening in Japan; however, sedation during EGD is not recommended. We aimed to assess the tolerability of unsedated EGD (USEGD) in the Japanese population. Methods Participants who underwent GC screening in Japanese urban areas between July 2021 and December ...
Kazuya Inoki, Toshiya Chiba, Kazuhiro Miura, Teppei Tagawa, Yutaka Aoyagi, Yoshiaki Takeuchi, Naoya Moriyama, Kensuke Kuraoka, Tadashi Ohara, Yuko Haruhara, Akira Mizuki, Jun Satio, Yoshimi Hagisawa, Naomi Ono, Noboru Takayama, Takeo Onishi, Akira Mishima, Norihiro Suzuki, Kazuo Kikuchi, Atsushi Katagiri, Fuyuhiko Yamamura, Sachiko Ohde, Eisuke Inoue, Takahisa Matsuda, Hitoshi Yoshida   +24 more
wiley   +1 more source

Is the incidence of early‐onset cancers increasing in the northeast of Italy? A 30‐year analysis of the regional cancer registration data by age, 1987–2019

International Journal of Cancer, Volume 158, Issue 3, Page 532-545, 1 February 2026.
Whats New? This observational study of the incidence trends of malignancy by site, stratified by age group and sex, over three decades in a large northern Italian population reveals a heterogeneous landscape among younger adults (aged under 50). Invasive cutaneous melanoma in both sexes, testicular cancer and multiple myeloma in males, and breast ...
Alessandra Buja, Chiara Trevisiol, Andrea Miatton, Stefano Guzzinati, Emanuela Bovo, Simone Mocellin, Alberto Fantin, Massimo Rugge, Vincenzo Bronte, Manuel Zorzi   +9 more
wiley   +1 more source