Results 131 to 140 of about 138,873 (259)

Reirradiation: Standards, challenges, and patient‐focused strategies across tumor types

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract Reirradiation (reRT), defined as administering a course of radiation therapy to a specific area previously irradiated, is an evolving treatment strategy for locoregionally recurrent cancer that offers significant potential and poses inherent challenges.
Arnaud Beddok, Jonas Willmann, Anna Embring, Ane L. Appelt, Panagiotis Balermpas, Kevin Chua, J. Isabelle Choi, Bernice Simone Elger, Dorota Gabrys, Peter Hoskin, Maximilian Niyazi, David Pasquier, Kelly Paradis, Orit Kaidar‐Person, Corien Plaisier, Nicole C. Schmitt, Conor E. Steuer, Juliette Thariat, Sue S. Yom, Philip Poortmans, Eliana Vasquez Osorio, Nicolaus Andratschke   +21 more
wiley   +1 more source

Update and new advances in fertility preservation and cancer

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract Adolescents and young adults with a cancer diagnosis face unique challenges during treatment and into survivorship related to fertility and family building. This review provides an updated overview of the impact of cancer and its associated treatments, including novel treatments in male and female fertility.
Gwendolyn P. Quinn, Michelle Bayefsky, Brooke Cherven, Lauren V. Ghazal, Kara N. Goldman, Nina Francis Levin, Leena Nahata, Bobby Najari, Sameer Thakker, Daniel R. Greenberg, Joshua A. Halpern, Susan T. Vadaparampil   +11 more
wiley   +1 more source

When Endoscopic Sedation is Not an Option: Insights From a Multicenter on‐site Survey on Tolerance for Japanese Gastric Cancer Screening

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Esophagogastroduodenoscopy (EGD) is widely used for gastric cancer (GC) screening in Japan; however, sedation during EGD is not recommended. We aimed to assess the tolerability of unsedated EGD (USEGD) in the Japanese population. Methods Participants who underwent GC screening in Japanese urban areas between July 2021 and December ...
Kazuya Inoki, Toshiya Chiba, Kazuhiro Miura, Teppei Tagawa, Yutaka Aoyagi, Yoshiaki Takeuchi, Naoya Moriyama, Kensuke Kuraoka, Tadashi Ohara, Yuko Haruhara, Akira Mizuki, Jun Satio, Yoshimi Hagisawa, Naomi Ono, Noboru Takayama, Takeo Onishi, Akira Mishima, Norihiro Suzuki, Kazuo Kikuchi, Atsushi Katagiri, Fuyuhiko Yamamura, Sachiko Ohde, Eisuke Inoue, Takahisa Matsuda, Hitoshi Yoshida   +24 more
wiley   +1 more source

Cervical metastasis of breast cancer: a case report and review of the literature

Discover Oncology
Metastatic breast cancer (BC) to the cervix is relatively rare among women with BC. Although the most common histopathological type of BC is invasive ductal carcinoma, invasive lobular carcinoma is more likely to metastasize to the female reproductive ...
Yuping Shan, Feng Hou, Yan Wang, Yi Han, Zhumei Cui, Guangjie Yin   +5 more
doaj   +1 more source

Clinical and genetic features of multiple primary tumours cohorts with a renal cell carcinoma: Implications for molecular genetic investigations

International Journal of Cancer, Volume 157, Issue 12, Page 2532-2543, 15 December 2025.
What's New? Current knowledge of the genetic architecture underlying the development of renal cell carcinoma‐related multiple primary tumours is limited. The authors comprehensively analysed the results of exome/genome sequencing cohorts including 534 patients to better define genotype–phenotype correlations.
Huairen Zhang, Bryndis Yngvadottir, Avgi Andreou, Yasemin Cole, Emma R. Woodward, James Whitworth, Eamonn R. Maher   +6 more
wiley   +1 more source

Desempenho do exame citológico e da captura híbrida II no rastreamento de lesões intraepiteliais escamosas de alto grau em mulheres HIV+

Cadernos de Saúde Pública
As lesões intraepiteliais escamosas de alto grau (HSIL) são precursoras do câncer do colo do útero, com maior risco de ocorrência e desenvolvimento em mulheres HIV+.
Letícia Martins Raposo, Luciane Velasque, Paula Mendes Luz, Ruth Khalili Friedman, Andrea Cytryn, Angela Cristina Vasconcelos de Andrade, Tazio Vanni, Pedro E. A. A. Brasil, Fabio Russomano, Valdiléa Gonçalves Veloso, Beatriz Grinsztejn, Claudio José Struchiner   +11 more
doaj  

Molecular analysis of the evolutionary history of endometrial and ovarian carcinoma in Lynch syndrome

International Journal of Cancer, Volume 157, Issue 11, Page 2294-2308, 1 December 2025.
What's New? Lynch syndrome is a prevalent cause of hereditary gynecological cancers, but the timeline of molecular alterations preceding malignancy remains unclear. By studying consecutive surveillance specimens for up to 15 years before cancer diagnosis, the authors found that atypical endometrial hyperplasia was indistinguishable from endometrial and
Anni K. Kauppinen, Alisa P. Olkinuora, Jukka‐Pekka Mecklin, Päivi T. Peltomäki   +3 more
wiley   +1 more source

A Machine Learning‐Optimized Immunogenic Cell Death Signature Reveals Tumor Immunogenicity and the Immunotherapy Response of Pancancer

MedComm – Future Medicine, Volume 4, Issue 4, December 2025.
This study introduces an innovative adversarial validation (AV) strategy integrated with machine learning to mitigate the problem of data set shift and enhance analyses of pan‐cancer immunogenicity. It identifies key immunogenic cell death‐related biomarkers and demonstrates their predictive potential for survival outcomes and responses to PD‐1 ...
Li Qiu, Danqing Huang, Yuening Zhang, Yingying Zhou, Ming Luo, Chengdong Zhang, Ying Huang, Mingyuan Zou, Wenlong Lu, Hui Liu, Shaowei Liu, Haoyang Huang, Kaiwen Ye, Yuan Hui, Cheng Tang, Zilong Yan, Xi Zhong, Zhiguo Luo, Hongxin Huang, Ming Zhou, Guangshuai Jia, Qibin Leng, Jun Liu   +22 more
wiley   +1 more source

Modulation of Autophagy by Ursolic and Betulinic Acids: Distinct Cytotoxic and Membrane‐Disruption in Malignant and Nonmalignant Cells

Cell Biology International, Volume 49, Issue 11, Page 1518-1536, November 2025.
ABSTRACT Autophagy is a critical adaptive mechanism in tumor cells that promotes survival under stress, but when dysregulated, it may trigger programmed cell death. The pentacyclic triterpenoids betulinic acid (BA) and ursolic acid (UA) are structurally related compounds that modulate autophagy; however, comparative insights into their effects on ...
Waleska Kerllen Martins, Tayana Mazin Tsubone, Chimara Emilia Nascimento Sanches, Cleidiane de Sousa Rocha, Ricardo Scarparo Navarro, Beatriz Simonsen Stolf, Susana Nogueira Diniz, Rosangela Itri, Mauricio S. Baptista   +8 more
wiley   +1 more source

Anticancer Potential of Wogonin: A Comprehensive Treatise

Food Science &Nutrition, Volume 13, Issue 11, November 2025.
Wogonin a plant flavonoid is abundantly found in the roots of Scutellaria baicalensis. In in vivo and in vitro investigations, it has immense therapeutic potential against different cancers including ovarian, colon, gastric, cervical, prostate, glioblastoma, head and neck cancer, hepatic cancer, leukemia, gastric, breast and kidney.
Hammad Naeem, Muhammad Shahbaz, Ushna Momal, Nimra Irshad, Muhammad Imran, Muzzamal Hussain, Tadesse Fenta Yehuala, Mohamed A. Abdelgawad, Ehab M. Mostafa, Mohammed M. Ghoneim, Samy Selim, Soad K. Al Jaouni, Suliman A. Alsagaby, Waleed Al Abdulmonem   +13 more
wiley   +1 more source