Results 51 to 60 of about 88,739 (232)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Factors Associated with Pain Levels During Office Hysteroscopy: A Cross-Sectional Study

Women
The goal of this study was to identify factors associated with pain sensitivity, procedural discomfort, and referral for surgical hysteroscopy, aiming to improve office hysteroscopy success rates.
Rafaela Tiemi Iwamoto Vicentin, Raphael Federicci Haddad, Julia Stamato de Figueiredo, Eric Katsuyama, Gustavo Yano Callado, Edward Araujo Júnior, Débora Davalos de Albuquerque Maranhão   +6 more
doaj   +1 more source

Епідеміологічні особливості поєднаних гіперпроліферативних процесів жіночої репродуктивної системи

Medičnì Perspektivi, 2013
The study involved 622 women of reproductive age with such hyperproliferative processes of the pelvic organs as uterine leiomyoma, endometrial hyperplasia and endometriosis. We studied main epidemiological factors inherent in these diseases.
V. H. Halytska, I. V. Ivach, Yu. V. Donska, V. O. Potapov, M. V. Medvedyev   +4 more
doaj   +1 more source

The Role of Sex Hormones in Inducing Maternal Uterine Remodeling and Vasodilation During Pregnancy [PDF]

, 2018
Uterine vascular adaptations such as vessel growth and vasodilation are needed to facilitate the more than 10-fold increase of uteroplacental blood flow (UPBF) during pregnancy.
Glessner-Fischer, Annie D.
core   +1 more source

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities [PDF]

, 2015
Background : Observational studies suggest higher pregnancy rates after the hysteroscopic removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine adhesions, which are detectable in 10% to 15% of women seeking treatment for ...
Bosteels, Jan, Broekmans, Frank J, D'Hooghe, Thomas M, Kasius, Jenneke, Mol, Ben Willem J, Weyers, Steven   +5 more
core   +2 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Ethno-Racial Differences in Age and Symptom Severity Among Pre-Menopausal Women Commencing Treatment for Benign Gynecological Conditions with a Levonorgestrel-Releasing Intrauterine Device

Health Equity
Introduction: Levonorgestrel-releasing intrauterine devices (LNG-IUDs) can be effective treatments for benign gynecological conditions, but there may be ethno-racial differences in how patients receive treatment.
Michael J. Green, Kemi M. Doll, Mollie E. Wood, Annie G. Howard, Lauren G. Anderson, Joacy G. Mathias, Natalie A. Rivadeneira, Erin T. Carey, Timothy S. Carey, Wanda Nicholson, Til Stürmer, Evan R. Myers, Whitney R. Robinson   +12 more
doaj   +1 more source

Diagnostic accuracy of sonohysterography vs hysteroscopy in benign uterine endocavitary findings [PDF]

, 2015
OBJECTIVE: To compare diagnostic accuracy of sonohysterography vs hysteroscopy in patients with benign uterine endocavitary findings. PATIENTS AND METHODS: This retrospective study evaluated 202 patients submitted to sonohysterography after transvaginal ...
Bianchi, Paola, Caserta, Donatella, Catalano, Angelica, Cozza, Giuliana, DI PROPERZIO, Matilde, Frega, Antonio, Gentile, M, Manzara, F, Marziani, Rosalia, Milazzo, Gn, Schimberni, Mauro, Torcia, Francesco, Zinna, M   +12 more
core