Results 121 to 130 of about 189,451 (295)

The Influence of Perceived Value, Customer Satisfaction, and Trust on Loyalty in Entertainment Platforms

open access: yesApplied Sciences
This study explores the intricate relationships between perceived value, customer satisfaction, trust, and loyalty in the context of the dynamic online entertainment platform industry.
Kyeongmin Yum, Jongnam Kim
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Aiming at understanding consumers´ behavior in fast food restaurants: a food values approach [PDF]

open access: yes, 2017
A partir de la clasificación de los valores alimenticios propuesta pertinente por Lusk y Briggeman (2009), este trabajo buscaba comprender el comportamiento de los consumidores en los restaurantes de comida rápida.
Izquierdo-Yusta, Alicia   +4 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Informational Foundation of the Human Act [PDF]

open access: yes, 2018
This book is the result of a collective research effort performed during many years in both Sweden and Spain. It is the result of attempting to develop a new field of research that could we denominate «human act informatics.» The goal has been to use the
de Marcos Ortega, Luis   +1 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Existence value, biodiversity, and the utilitarian dilemma

open access: yes, 2017
Existence value has been argued to be a significant part of the total economic value of some ecosystems. However, its compatibility with the welfare economic foundations of economic valuation is very limited – it is difficult to logically conceive of changes in existence. Moreover, when applied to biodiversity, the concept of existence value gives rise
openaire   +2 more sources

THE INFLUENCE OF HEDONIC VALUE AND UTILITARIAN VALUE ON PURCHASING DECISIONS FOR SAMSUNG SMARTPHONES

open access: yesSULTANIST: Jurnal Manajemen dan Keuangan
In the modern era, technological advances are the main factor driving changes in various aspects of human life. The rapid development of technology today allows people to access information easily through various media, such as using smartphones so that it becomes a human need, especially among students.
Anugrah Bayu Santoso   +1 more
openaire   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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