Results 101 to 110 of about 189,451 (295)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
An Environmental-Economic Measure of Sustainable Development [PDF]
A central issue in the study of sustainable development is the interplay of growth and sacrifice in a dynamic economy. This paper investigates the relationship among current consumption, growth, and sustained consumption in two canonical, stylized ...
Robert D. Cairns, Vincent Martinet
core
The organisational goals of social entrepreneurs: how social are they? [PDF]
, 2010 There is an increasing consensus among academics that the common denominator of ‘social entrepreneurs’ is their adherence to a ‘dominant social mission’.
Moray, Nathalie, Stevens, Robin
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
An Incongruent Amalgamation: John Stuart Mill\u27s Utilitarianism on Naturalism [PDF]
, 2015 John Stuart Mill\u27s utilitarian principle of the greatest happiness for the greatest number, often surfaces in cultural debates in the contemporary West over the extent and foundations of moral duties.
Robinson, Jeffrey M
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Management şi Marketing, 2018 The present study has attempted to create and examine a conceptually grounded working model that examines the moderating influence of utilitarian and hedonic shopping values with Indian grocery stores on the association between usage of Private Label (PL)
Bhat Ishfaq Hussain, Singh Sapna
doaj +1 more source
Utilitarian Reasoning in Nazi Medical Policy: Some Preliminary Investigations [PDF]
, 1975 Roll 102b. Walsh Hall #2. Image 15 of 47. (29 January, 1954) [PHO 1.102b.15]The Boleslaus Lukaszewski (Father Luke) Photographs contain more than 28,000 images of Saint Louis University people, activities, and events between 1951 and 1970.
LaChat, Michael R.
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source