Results 81 to 90 of about 5,705,691 (289)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2018 Orientasi pelanggan merupakan faktor kunci keberhasilan pemasaran modern. Setiap organisasi atau perusahaan wajib menggunakan sudut pandang konsumen dalam merencanakan dan mengorganisasikan aktivitas-aktivitas pemasarannya.
NUDIN, Intan Aprillia
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A benefit congruency framework of sales promotion effectiveness [PDF]
Are monetary savings the only explanation for consumer response to a sales promotion ? If not, how do the different consumer benefits of a sales promotion influence its effectiveness ?
CHANDON, Pierre +2 more
core
Pengaruh Utilitarian Value, Hedonic Value, dan Symbolic Value Terhadap Kepuasan Konsumen Minimarket di Kota Surakarta [PDF]
, 2020 The purpose of this study is to determine the effect of utilitarian value, hedonic value, and symbolic value on customer satisfaction. Population in this study are consumers who have shopped at minimarket in the region of Surakarta City.
, Ihwan Susila, SE., M.Si., Ph.D +1 more
core +1 more source
Sketsa BisnisIntroduction, this study aims to examine the effects of utilitarian value, hedonic value, and online review on repurchase intention, with satisfaction serving as a mediating variable among fashion and beauty e-commerce users in Batam City.
Fitriana aidnilla Sinambela +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Twofold Optimality of the Relative Utilitarian Bargaining Solution [PDF]
Given a bargaining problem, the `relative utilitarian' (RU) solution maximizes the sum total of the bargainer's utilities, after having first renormalized each utility function to range from zero to one. We show that RU is `optimal' in two very different
Pivato, Marcus
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source