Results 91 to 100 of about 3,565,302 (299)
Future Utility Analysis Research: Continue, but Expand the Cognitive and Strategic Focus [PDF]
[Excerpt] Does utility analysis research have a future? I believe the answer depends on how we contemplate the nature of such research. The distinction between two potential paths has never been more apparent. On the one hand, as researchers, industrial
Boudreau, John W.
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Image and Reality: the Case of Job Satisfaction [PDF]
This study makes a distinction between two types of utility. Experienced utility is defined as the job satisfaction derived from the present job, estimated by using a subjective evaluation of job satisfaction.
Ferrer-i-Carbonell, Ada +2 more
core
Facelifting in Utility Maximization
We establish the existence and characterization of a primal and a dual facelift - discontinuity of the value function at the terminal time - for utility-maximization in incomplete semimartingale-driven financial markets.
Larsen, Kasper +2 more
core +1 more source
Utility Manning: Young Filipino Men, Servitude and the Moral Economy of Becoming a Seafarer and Attaining Adulthood [PDF]
To get a job as a seafarer in the global maritime industry, thousands of male Filipino youths work for free as ‘utility men’ for manning agencies that supply seafarers to ship operators around the world.
Galam, Roderick G.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Expected utility without utility [PDF]
This paper advances an interpretation of Von Neumann–Morgenstern’s expected utility model for preferences over lotteries which does not require the notion of a cardinal utility over prizes and can be phrased entirely in the language of probability ...
Erio Castagnoli, Marco LiCalzi
core
The time resolution of the St. Petersburg paradox
A resolution of the St. Petersburg paradox is presented. In contrast to the standard resolution, utility is not required. Instead, the time-average performance of the lottery is computed.
Boltzmann L. +15 more
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source

