Results 81 to 90 of about 3,565,302 (299)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Applied SciencesThe development of cracks and solution cavities in carbonate reservoirs can notably reduce the rock’s mechanical properties, leading to a severe wellbore collapse problem during drilling operations.
Jingzhe Zhang +6 more
doaj +1 more source
Utility maximization with current utility on the wealth: regularity of solutions to the HJB equation [PDF]
, 2015 We consider a utility maximization problem for an investment-consumption portfolio when the current utility depends also on the wealth process. Such kind of problems arise, e.g., in portfolio optimization with random horizon or with random trading times.
Federico, Salvatore +2 more
core +2 more sources
The utility of utility indices [PDF]
Bulletin of the Psychonomic Society, 1978 Many researchers have questioned the incorporation of utility indices following significant results yielded by the F ratio. Problems frequently mentioned concerning magnitude estimates include biases, questionable model utilization, acceptable size of the UI, and effects of sample size.
David R. Soderquist, Richard A. Hussian
openaire +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Utility maximization in incomplete markets
, 2005 We consider the problem of utility maximization for small traders on incomplete financial markets. As opposed to most of the papers dealing with this subject, the investors' trading strategies we allow underly constraints described by closed, but not ...
Hu, Ying +2 more
core +1 more source
Reverse Engineering TCP/IP-like Networks using Delay-Sensitive Utility Functions [PDF]
, 2007 TCP/IP can be interpreted as a distributed primal-dual algorithm to maximize aggregate utility over source rates. It has recently been shown that an equilibrium of TCP/IP, if it exists, maximizes the same delay-insensitive utility over both source ...
Low, Steven H., Pongsajapan, John
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Simon Grant, Monti, Martin Osherson, Daniel [PDF]
The classical theory of preference among monetary bets represents people as expected utility maximizers with nondecreasing concave utility functions. Critics of this account often rely on assumptions about preferences over wide ranges of total wealth. We
A Note on Concave Utility Functions
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