Results 131 to 140 of about 1,359,991 (293)
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
A mixed-utility theory of vote choice regret. [PDF]
Public Choice, 2018 Bol D, Blais A, Laslier JF.
europepmc +1 more source
Cumulative Prospect Theory for Parametric and Multiattribute Utilities [PDF]
In cumulative prospect theory models, different behavior concerning gains and losses is per-mitted. For gains different decision weights are assigned than for losses, and the shape of utility can reveal loss aversion.
Zank,H.
core +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Scalar utility theory and proportional processing: What does it actually imply? [PDF]
J Theor Biol, 2016 Rosenström T, Wiesner K, Houston AI.
europepmc +1 more source
Multi-Criteria Analysis of Factors Use Level: The Case of Water for Irrigation [PDF]
In this paper we present a methodology to analyse input use in the agricultural sector. The novelty of the theoretical model explained is that it has been developed considering a multi-criteria environment.
José A. Gómez-Limón +2 more
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FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Measuring risk attitudes among Mozambican farmers: [PDF]
Although farmers in developing countries are generally thought to be risk averse, little is known about the actual form of their risk preferences. In this paper, we use a relatively large field experiment to explore risk preferences related to sweet ...
de Brauw, Alan, Eozenou, Patrick
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