Results 51 to 60 of about 6,400,365 (286)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
The multiple values of nature show the lack of a coherent theory of value—In any context
People and NaturePathways to sustainability require a broader and fuller representation of the multiple values of nature in policy and practice. In this People and Nature special feature entitled ‘The Multiple Values of Nature’, researchers interpreted all three key ...
Kai M. A. Chan +5 more
doaj +1 more source
BUILDING AND DEVELOPING A PROJECT TEAM ON THE BASIS OF A MULTICRITERIA MODEL
Сучасний стан наукових досліджень та технологій в промисловості, 2017 The subject matter of the article is mathematical models for solving particular problems of selecting candidates for building a project team. The goal is to develop formalized models and methods for assessing the level of the generalized social and ...
Nataliia Kosenko, Alona Kolomiiets
doaj +1 more source
CIB - UTILITY BASED SYSTEMS FRAMEWORK FOR EXISTING RESIDENTIAL BUILDING
Journal of Asian Architecture and Building Engineering, 2022 This study proposes an approach for conducting comparative assessments between renovation and new construction through the use of CIB utility theory systems and applies the methodology to an adaptive case study. To this end, the theoretical underpinnings
Ching-Chi Lin +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
THE VALUE OF MONEY AND THE FLAW-OF-AVERAGES
South African Journal of Industrial Engineering, 2018 Given the state of uncertainty in the world, decision analysis and decision-making under conditions of uncertainty are becoming more important. However, any rational decision-making requires a criterion on which to base the decision — which implies the ...
Kruger, Paul , Yadavalli, Sarma
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International Journal of Agricultural Sustainability, 2022 Achieving a sustainable agricultural system requires an effective assessment of economic, environmental, and social conditions. Existing research has mainly focused on a single sector and lacks critical comparisons of determinants and trade-offs between ...
Carlos Moreno-Miranda, Liesbeth Dries
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Open Questions in Utility Theory [PDF]
, 2020 Throughout this paper, our main idea is to explore different classical questions arising in Utility Theory, with a particular attention to those that lean on numerical representations of preference orderings. We intend to present a survey of open questions in that discipline, also showing the state-of-art of the corresponding literature.
Campión Arrastia, María Jesús +1 more
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source