Results 51 to 60 of about 1,359,991 (293)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Evaluating gambles using dynamics

open access: yes, 2015
Gambles are random variables that model possible changes in monetary wealth. Classic decision theory transforms money into utility through a utility function and defines the value of a gamble as the expectation value of utility changes. Utility functions
Gell-Mann, Murray, Peters, Ole
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The multiple values of nature show the lack of a coherent theory of value—In any context

open access: yesPeople and Nature
Pathways to sustainability require a broader and fuller representation of the multiple values of nature in policy and practice. In this People and Nature special feature entitled ‘The Multiple Values of Nature’, researchers interpreted all three key ...
Kai M. A. Chan   +5 more
doaj   +1 more source

BUILDING AND DEVELOPING A PROJECT TEAM ON THE BASIS OF A MULTICRITERIA MODEL

open access: yesСучасний стан наукових досліджень та технологій в промисловості, 2017
The subject matter of the article is mathematical models for solving particular problems of selecting candidates for building a project team. The goal is to develop formalized models and methods for assessing the level of the generalized social and ...
Nataliia Kosenko, Alona Kolomiiets
doaj   +1 more source

Optimal Payoffs under State-dependent Preferences

open access: yes, 2014
Most decision theories, including expected utility theory, rank dependent utility theory and cumulative prospect theory, assume that investors are only interested in the distribution of returns and not in the states of the economy in which income is ...
Bernard, Carole   +3 more
core   +3 more sources

Neurobiological studies of risk assessment: A comparison of expected utility and mean-variance approaches [PDF]

open access: yes, 2008
When modeling valuation under uncertainty, economists generally prefer expected utility because it has an axiomatic foundation, meaning that the resulting choices will satisfy a number of rationality requirements.
Bossaerts, Peter, d'Acremont, M.
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

THE VALUE OF MONEY AND THE FLAW-OF-AVERAGES

open access: yesSouth African Journal of Industrial Engineering, 2018
Given the state of uncertainty in the world, decision analysis and decision-making under conditions of uncertainty are becoming more important. However, any rational decision-making requires a criterion on which to base the decision — which implies the ...
Kruger, Paul , Yadavalli, Sarma
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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