Results 71 to 80 of about 6,400,365 (286)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A cumulative prospect theory approach to car owner mode choice behaviour prediction

open access: yesTransport, 2014
The uncertain transportation environment makes travel’s mode choice decision-making behaviour become a complex and alterable process. Based on the cumulative prospect theory, this paper analysed the long-standing use of utility theory for the travel’s ...
Shi An, Xiaowei Hu, Jian Wang
doaj   +1 more source

Other title: Senate Bill 261 - Testimony on Behalf of the Citizens' Utility Ratepayer Board by David Springe, Consumer Counsel

open access: yes, 2015
application/pdf; "March 19, 2015."; Testimony before the Kansas Legislature, Senate Assessment and Taxation Committe, presented by David Springe, Consumer Counsel, Citizens' Utility Ratepayer Board.Testimony in opposition to Senate Bill 261 ...
Springe, David.
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Pricing Model Study of Shared Parking Area Charge Based on Game Theory

open access: yesSystems
In this study, a tripartite decision-making parking pricing model was developed based on Game Theory to comprehensively reflect the impact of parking pricing on private car travelers, parking lot operators, and traffic managers.
Chao Sun, Haodong Jing, Haowei Yin
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Other title: House Bill 2806 - Testimony on Behalf of the Citizens' Utility Ratepayer Board by David Springe, Consumer Counsel

open access: yes, 2008
application/pdf; "February 19, 2008."; Testimony before the Kansas Legislature, House Utilities Committee, presented by David Springe, Consumer Counsel, Citizens' Utility Ratepayer Board.Testimony in opposition to House Bill 2806.
Springe, David.
core   +1 more source

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