Results 51 to 60 of about 1,624,767 (350)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

UV Fingerprinting Approaches for Quality Control Analyses of Food and Functional Food Coupled to Chemometrics: A Comprehensive Analysis of Novel Trends and Applications

open access: yesFoods, 2022
(1) Background: Ultraviolet-visible (UV-Vis) spectroscopy is a common analytical tool to detect chromophore in compounds by monitoring absorbance spectral wavelengths.
Mohamed A. Farag   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Photodegradation Pathways of Typical Phthalic Acid Esters Under UV, UV/TiO2, and UV-Vis/Bi2WO6 Systems

open access: yesFrontiers in Chemistry, 2019
Photolysis and photocatalysis of typical phthalic acid esters (dimethyl phthalate, DMP; diethyl phthalate, DEP; dibutyl phthalate, DBP) were carried out in UV, UV/TiO2, and UV-Vis/Bi2WO6 systems.
Chunying Wang   +6 more
doaj   +1 more source

Spectroscopy of Stardust from 200nm to 16µM (with a gap in the middle) [PDF]

open access: yes, 2006
UV/Vis and IR spectroscopy are complementary, non-destructive techniques that can be used to identify the presence of a range of organic and inorganic, hydrated and anhydrous minerals within micron-sized grains.
Fernandes, C.   +3 more
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Sensitive and accurate dual wavelength UV-VIS polarization detector for optical remote sensing of tropospheric aerosols

open access: yes, 2012
An UV-VIS polarization Lidar has been designed and specified for aerosols monitoring in the troposphere, showing the ability to precisely address low particle depolarization ratios, in the range of a few percents.
David, G.   +3 more
core   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Luwak Coffee Classification Using UV-Vis Spectroscopy Data: Comparison of Linear Discriminant Analysis and Support Vector Machine Methods

open access: yesAceh International Journal of Science and Technology, 2018
UV-Vis spectroscopy has been used as a promising method for coffee quality evaluation including in authentication of several high-economic coffee types.
Diding Suhandy, Meinilwita Yulia
doaj   +1 more source

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