Results 141 to 150 of about 31,082 (256)

RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation

Photochemistry and Photobiology, EarlyView.
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan, Angitha Nair, M. Alexandra Carpenter, Michael G. Kemp   +3 more
wiley   +1 more source

NAMPT Deficiency Promotes Endothelial-Mesenchymal Transition by Inhibiting Energy Metabolism and Lysosomal Acidification in Late-Onset Fuchs Endothelial Corneal Dystrophy. [PDF]

Invest Ophthalmol Vis Sci
Xie L, Chen M, Wu J, Li Z, Guo R, Yu H, Li X, Wang Q, Liu F, Wang J, Wang L.   +10 more
europepmc   +1 more source

Measurement and modeling of diffuse ultraviolet radiation: A review

Photochemistry and Photobiology, EarlyView.
Solar UV radiation consists of direct and diffuse UV components. The diffuse component contributes to the exposure received by humans and to the risk of skin cancer and sun‐related eye disorders. This review aims to determine future research directions for the measurement and modeling of diffuse solar UV radiation.
Alfio V. Parisi, Joanna Turner, Abdurazaq Amar, Damien P. Igoe, Peter Schouten, Nawin Raj, Nathan Downs, Harry Butler   +7 more
wiley   +1 more source

Photoprotective potential of gadusol against ultraviolet B radiation in melanocytes

Photochemistry and Photobiology, EarlyView.
Gadusol protects melanocytes from ultraviolet B (UVB)‐induced damage without cytotoxicity. Abstract The increasing incidence of skin cancer, including melanoma, combined with the need for ultraviolet (UV) filters that are safe for human health and marine ecosystems, is driving the search for new photoprotective agents.
Andressa Mai Matsumoto, Rocío Isla Naveira, Andy Joel Taipe Huisa, Marcelo Augusto Germani Marinho, Lais Zortéa, José María Monserrat, Agueda Elena Massa, María Sandra Churio, Ana Paula de Souza Votto   +8 more
wiley   +1 more source

Molecular Identification and Characterisation of a Spiro-Indoline-Benzoxadiazine Derivative for Photochromic Textile Sensors. [PDF]

Int J Mol Sci
Sąsiadek-Andrzejczak E, Jaszczak-Kuligowska M, Safandowska M, Kozicki M, Rokita B, Florentino-Madiedo L, Barburski M, Ranz D, Mallada R.   +8 more
europepmc   +1 more source

Zebrafish as a practical and convenient model for the study of photodynamic and photothermal therapy of solid tumors: A scoping review

Photochemistry and Photobiology, EarlyView.
Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...
Ethan Wilson, Alexander Fiorentino, Brian W. Booth, Valery Bliznyuk, Diana Ivankovic, Luigi Boccuto   +5 more
wiley   +1 more source

Reactive oxygen species accelerated glycation for oxygen-independent corneal cross-linking. [PDF]

Front Bioeng Biotechnol
Fan J, Vukelic S.
europepmc   +1 more source

Advances in organic UV filters for sunscreens over the past decade

Photochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon, Maria Carolina Theisen, Andressa Motta Castro, Giovana Jones Radke, Fernando Fumagalli   +4 more
wiley   +1 more source

Photoprotection of a novel resveratrol analogue: insights from 2D, 3D, and endothelialized bioprinted human skin models. [PDF]

Front Pharmacol
Pasuch Gluzezak AJ, Essayan L, Thomann C, Dos Santos JL, Marquette CA, Gaspar LR.   +5 more
europepmc   +1 more source

Antimicrobial photodynamic therapy in Candida spp. biofilms: In vitro and in vivo protocols

Photochemistry and Photobiology, EarlyView.
This review addresses the critical challenges in translating in vitro antimicrobial photodynamic therapy protocols to in vivo models, with a particular focus on the hurdles of standardization. The vast diversity in photosensitizers and light parameters across different target cells and models requires a rigorous optimization process.
Lívia Mara Alves Figueiredo‐Godoi, Ana Júlia Barbosa Tomé, Cristina Kurachi   +2 more
wiley   +1 more source