Results 71 to 80 of about 153,159 (379)

Microbiome and Autoimmune Uveitis

Frontiers in Immunology, 2019
Commensal microbes affect all aspects of immune development and homeostasis in health and disease. Increasing evidence points to the notion that the gut commensals impact not only intestinal diseases but also diseases in tissues distant from the gut ...
Reiko Horai, Rachel R. Caspi
semanticscholar   +1 more source

Drug-induced uveitis: A review

Indian Journal of Ophthalmology, 2020
Uveitis maybe induced by the use of various medications known as drug-induced uveitis (DIU), though rare it is an important cause of uveitis which one needs to be aware of.
M. Agarwal, Parthopratim Dutta Majumder, K. Babu, V. Konana, M. Goyal, S. Touhami, D. Stanescu-Segall, B. Bodaghi   +7 more
semanticscholar   +1 more source

Hexokinase‐2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming

Advanced Science, EarlyView.
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang, Yining Sun, Xintong Yu, Ruoqi Wang, Yuting Zhang, Jinjie Yu, Shuang Xie, Yujia Cai, Yuhong Luo, Wei Chen   +9 more
wiley   +1 more source

Metagenomic deep sequencing of aqueous fluid detects intraocular lymphomas. [PDF]

, 2017
IntroductionCurrently, the detection of pathogens or mutations associated with intraocular lymphomas heavily relies on prespecified, directed PCRs. With metagenomic deep sequencing (MDS), an unbiased high-throughput sequencing approach, all pathogens as ...
Acharya, Nisha, Bloomer, Michele, DeRisi, Joseph L, Doan, Thuy, Gonzales, John, Shantha, Jessica G, Wilson, Michael R   +6 more
core   +1 more source

The Clinical Spectrum and Outcomes of Ocular Syphilis in Saudi Arabia: The Emergence of a Uveitic Masquerader

Journal of Epidemiology and Global Health
This retrospective multicenter cohort study aimed to describe the clinical features and report the outcomes of the management of ocular syphilis in Saudi Arabia.
Abrar A. Alhawsawi, Abeer Aljahdali, Enas Magharbil, Asma Alzuabi, Abdulrahman F. Albloushi, Dhoha Alhamad, Abrar K. Alsalamah, Sulaiman M. Alsulaiman, Fatimah Al Hammad, Moustafa S. Magliyah, Hassan A. Al-Dhibi   +10 more
doaj   +1 more source

Cytokine Profiling in Aqueous Humor Samples From Patients With Non-Infectious Uveitis Associated With Systemic Inflammatory Diseases

Frontiers in Immunology, 2020
Non-infectious uveitis are intraocular inflammatory conditions caused by dysregulated activation of the immune response without any detectable infectious agents.
M. Bonacini, A. Soriano, L. Cimino, L. de Simone, E. Bolletta, F. Gozzi, F. Muratore, M. Nicastro, L. Belloni, A. Zerbini, L. Fontana, C. Salvarani, S. Croci   +12 more
semanticscholar   +1 more source

Magnetically Controllable and Degradable Milliscale Swimmers as Intraocular Drug Implants

Advanced Science, EarlyView.
Magnetically controllable degradable milliscale swimmers (MDMS) offer a promising alternative to commercial intraocular drug implants, reducing complications like implant dislocation and uncontrolled drug release. MDMS achieve high velocities in ocular environments, enable real‐time imaging, and deliver drugs effectively without disrupting retinal ...
Erdost Yildiz, Ugur Bozuyuk, Eray Yildiz, Fan Wang, Mertcan Han, Alp Can Karacakol, Devin Sheehan, Yan Yu, Metin Sitti   +8 more
wiley   +1 more source

Pattern of uveitis in a tertiary eye care center of central India: Results of a prospective patient database over a period of two years

Indian Journal of Ophthalmology, 2020
Purpose: To identify the pattern of uveitis at a tertiary eye center in the central India and to compare with other reported studies. Methods: This prospective observational study was undertaken with all new uveitis cases attending the uvea clinic ...
Prashant Borde, Priyanka, Kavita Kumar, Brijesh Takkar, Bhavana Sharma   +4 more
doaj   +1 more source

Human Immunodeficiency Virus and Uveitis

Viruses, 2023
Uveitis is one of the most common ocular complications in people living with the Human immunodeficiency virus (HIV) and can be classified into HIV-induced uveitis, co-infection related uveitis, immune recovery uveitis, and drug-induced uveitis.
Mingming Yang, Koju Kamoi, Yuan Zong, Jing Zhang, Kyoko Ohno-Matsui   +4 more
doaj   +1 more source

Artificial Intelligence‐Driven Proteomics Identifies Plasma Protein Signatures for Diagnosis and Stratification of Behçet's Disease

Advanced Science, EarlyView.
Molecular and functional landscape of BD progression and severity based on in‐depth proteomics. Tree boosting machine learning models with favorable performance in BD diagnosis and stratification. Efficient biomarker panels for BD diagnosis and stratification. .
Linlin Cheng, Mansheng Li, Zhou Bai, Xiaobo Yu, Wenjie Zheng, Yongzhe Li, Yudong Liu   +6 more
wiley   +1 more source