Results 71 to 80 of about 120,128 (345)

Persistent clinical efficacy and safety of anti-tumour necrosis factor \textgreeka therapy with infliximab in patients with ankylosing spondylitis over 5 years: evidence for different types of response [PDF]

, 2008
Background: There is insufficient evidence for the long-term efficacy and safety of anti-tumour necrosis factor therapy in patients with ankylosing spondylitis (AS).
Alten, R., Baraliakos, X., Braun, J., Burmester, G., Fritz, C., Krause, A., Listing, J., Schewe, Stefan, Schneider, M., Sieper, J., Sörensen, H., Zeidler, H.   +11 more
core   +1 more source

The Impact of Nonsteroidal Anti‐Inflammatory Drugs on Radiographic Spinal Progression in Patients With Axial Spondyloarthritis: 10‐Year Results From an Inception Cohort

Arthritis &Rheumatology, EarlyView.
Objective This study aims to investigate the impact of nonsteroidal anti‐inflammatory drug (NSAID) intake on radiographic spinal progression in axial spondyloarthritis (axSpA), considering different NSAID types (COX‐2 inhibitors [COX2i] and nonselective NSAIDs [ns‐NSAIDs]) and disease subgroups (radiographic [r‐axSpA] and nonradiographic [nr‐axSpA ...
Murat Torgutalp, Valeria Rios Rodriguez, Fabian Proft, Mikhail Protopopov, Judith Rademacher, Hildrun Haibel, Joachim Sieper, Martin Rudwaleit, Denis Poddubnyy   +8 more
wiley   +1 more source

Findings of ocular and brain hemodynamics in patients with anterior uveitis complicated by macular edema

Journal of Ophthalmology, 2020
Background: Uveitis is the fifth most common cause of visual loss in the developed world, accounting for about 10% of legal blindness. Macular edema (ME) has been found to be the most important cause of both blindness and visual impairment (29% and 41 ...
N.I. Khramenko, N.V. Konovalova
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Vogt-Koyanagi-Harada Syndrome in a 10 Years Old Child [PDF]

, 2011
The Vogt-Koyanagi-Harada (VKH) syndrome is a rare systemic disorder of uveitis, dysacousia, vitiligo, premature graying of the hair, eyebrows and eyelashes, and meningoencephalitis. Although frequently unrecognised,VKH may affect children.
Singh, T, Sufi, AR, Zargar, S
core   +1 more source

Influence of FK 506 (tacrolimus) on circulating CD4 ⁺ t cells expressing cd25 and cd45ra antigens in 19 patients with chronic progressive multiple sclerosis participating in an open label drug safety trial [PDF]

, 1994
We have taken the opportunity of a clinical trial of the potential efficacy and safety of FK 506 (tacrolimus) in chronic progressive multiple sclerosis (MS) to examine the influence of this potent new immunosuppressant on circulating T-lymphocytes in an ...
A. W. Thomson, Abu-Elmagd K., B. Eidelman, B. Lemster, Collett D, Eidelman B H., Ellison G W., Emry P., Fung J J., H. R. Rilo, Hafler D A., Hafler D A., Hauser S L., Hintzen R Q., Hofman F M., J. J. Fung, J. Woo, Japanese FK, K. Abu-Elmagd, Kino T., Kurtzke J F, L. L. Huang, Lebranchu Y., Lemster B., Lemster B., McCauley J., McMichael J., Mochizuki M., Mortimoto C, N. Johnson, P. B. Carroll, R. Russell-Hall, Rose L M., Starzl T E., T. E. Starzl, Tamura K., The Multiple Sclerosis Study Group, Thomson A V., Thomson A W, Thomson A W., Thomson A W., Thomson A W., Tocci M J., W. Irish, Woo J., Woo J., Zeevi A.   +46 more
core   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Clinical and imaging characteristics of neuroretinitis secondary to cat scratch disease from tertiary centers in Malaysia: a retrospective study

Journal of Ophthalmic Inflammation and Infection
Background Cat scratch disease (CSD) is the commonest etiology of neuroretinitis (NR) and is caused by Bartonella henselae. The objective of this study was to look at clinical, imaging characteristics and outcomes among serology confirmed Cat scratch ...
Rajasudha Sawri Rajan, Sangeeta Kuganasan, Nazima Shadaht Ali, Roslin Azni Abdul Aziz, Shelina Oli Mohamed   +4 more
doaj   +1 more source

Voclosporin‐induced gingival enlargement: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca, Jessica M. Greco, Dimitris N. Tatakis   +2 more
wiley   +1 more source

Pattern of uveitis in a tertiary eye care center of central India: Results of a prospective patient database over a period of two years

Indian Journal of Ophthalmology, 2020
Purpose: To identify the pattern of uveitis at a tertiary eye center in the central India and to compare with other reported studies. Methods: This prospective observational study was undertaken with all new uveitis cases attending the uvea clinic ...
Prashant Borde, Priyanka, Kavita Kumar, Brijesh Takkar, Bhavana Sharma   +4 more
doaj   +1 more source