Results 51 to 60 of about 78,339 (310)

Delayed-onset cytomegalovirus retinitis after 0.2 µg/day fluocinolone acetonide implantation: a case series

Journal of Ophthalmic Inflammation and Infection
Purpose To describe the clinical features and outcomes of cytomegalovirus retinitis (CMVR) presenting after intravitreal fluocinolone acetonide (FAc) implantation.
Anamika Patel, Ilaria Testi, Carlos Pavesio   +2 more
doaj   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

The Clinical Spectrum and Outcomes of Ocular Syphilis in Saudi Arabia: The Emergence of a Uveitic Masquerader

Journal of Epidemiology and Global Health
This retrospective multicenter cohort study aimed to describe the clinical features and report the outcomes of the management of ocular syphilis in Saudi Arabia.
Abrar A. Alhawsawi, Abeer Aljahdali, Enas Magharbil, Asma Alzuabi, Abdulrahman F. Albloushi, Dhoha Alhamad, Abrar K. Alsalamah, Sulaiman M. Alsulaiman, Fatimah Al Hammad, Moustafa S. Magliyah, Hassan A. Al-Dhibi   +10 more
doaj   +1 more source

Guidance on Noncorticosteroid Systemic Immunomodulatory Therapy in Noninfectious Uveitis: Fundamentals Of Care for UveitiS (FOCUS) Initiative [PDF]

, 2018
TOPIC: An international, expert-led consensus initiative to develop systematic, evidence-based recommendations for the treatment of noninfectious uveitis in the era of biologics.
Al-Dhibi, Hassan A., Rosenbaum, James T., Rosenbaum, James T, Al-Dhibi, HA, Belfort, R., Jr, Belfort Rubens, Chee, Soon Phaik, Dick, Andrew D, Al-Dhibi, H.A., Belfort, R, Nascimento, Heloisa, Nascimento, H., Brezin, Antoine P, Davis, JL, Ramanan, Athimalaipet V, Carreño, E, Brezin, Antoine P., Salek, S, Siak, Jay, Sonoda, Koh-Hei, Nascimento, H, Davis, Janet L., Al-Dhibi, Hassan A, Dick, AD, Chee, SP, Chee, S.P., Fundamentals of Care for Uveitis International Consensus Group, Rosenbaum, J.T., Salah, S, Brézin, AP, Siak, J., Belfort, Rubens, Salah, Sawsen, Steeples, L, Carreno, Ester, Ramanan, AV, Sonoda, K-H, Dick, A.D., Salah, S., Salek, S., Ramanan, A.V., Siak, J, Davis, Janet L, Ramanan, Athimalaipet V., Rosenbaum, JT, Steeples, Laura, Carreño, E., Belfort, Rubens, Jr. [UNIFESP], Dick, Andrew D., Steeples, L., Salek, Sherveen, Cons, Fundamentals Care Uveitis Int, Davis, J.L., Brézin, A.P., Sonoda, K.H., Nascimento, Heloisa [UNIFESP]   +55 more
core   +2 more sources

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Acral Lentiginous Melanoma With NRAS Mutation and Ocular Surface Toxicity Following Immunotherapy and Investigational KRASG12C Inhibitor: Case Report

Case Reports in Oncological Medicine
We report the case of a patient with metastatic foot melanoma enrolled in a clinical trial of the anti-RAS agent RMC-6236 who developed chronic bilateral corneal epithelial defects and thinning, likely secondary to the systemic effects of targeted ...
Elisah Huynh, Andrew Gregory, Peter Y. Chang   +2 more
doaj   +1 more source

Rational management of uveitis [PDF]

, 1976
CITATION: Ancker, E., Molteno, A. C. B. & Straughan, J. L. Rational management of uveitis. South African Medical Journal, 50(9):286-288.The original publication is available at http://www.samj.org.zaEndogenous uveitis is an important cause of blindness ...
Straughan, J. L., Molteno, A. C. B., Ancker, E.   +2 more
core  

The standardisation of uveitis nomenclature (SUN) project

, 2022
The uveitides are a collection of over 30 diseases characterised by intraocular inflammation. Previous work demonstrated that the agreement among uveitis experts on diagnosis was modest at best with some pairs of experts having chance alone agreement on ...
Standardization Uveitis Nomenclatu, Jabs, Douglas A., Palestine, Alan G., Galor, Anat, Thorne, Jennifer E., Davis, Janet, McCluskey, Peter   +6 more
core   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

The effect of anti-TNF α therapy on refractory non-infectious pediatric uveitis in Saudi Arabia

BMC Ophthalmology
Purpose To report the outcomes of anti-tumor necrosis factor alpha (anti-TNF-α) treatment in children with refractory non-infectious uveitis. Methods Retrospective chart review for all children aged ≤ 18 years, diagnosed to have non-infectious uveitis ...
Abeer Aljahdali, Abrar A. Alhawsawi, Maram Alenazi, Moustafa S. Magliyah, Hassan Al-Dhibi   +4 more
doaj   +1 more source