Results 61 to 70 of about 78,339 (310)

Optical coherence tomography angiography (OCTA) of retinal vasculature in patients with post fever retinitis: a qualitative and quantitative analysis

Scientific Reports, 2021
Post fever retinitis is a heterogenous entity that is seen 2–4 weeks after a systemic febrile illness in an immunocompetent individual. It may occur following bacterial, viruses, or protozoal infection. Optical coherence angiography (OCTA) is a newer non-
Srinivasan Sanjay, Santosh Gopi Krishna Gadde, Sameeksha Agrawal, Padmamalini Mahendradas, Nivedhitha Govindaswamy, Ankush Kawali, Chaitra Jayadev, Sajjan Sangai, Abhijit Sinha Roy, Rohit Shetty   +9 more
doaj   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

A case of hypertensive uveitis with intravitreal faricimab

, 2023
PURPOSE: To report a novel case of hypertensive uveitis with intravitreal faricimab. METHODS: This is a case report. A 69-year-old female undergoing treatment of bilateral diabetic macular oedema with intravitreal faricimab presented for routine review ...
McAllister, Andrew, Kitson, Samantha
core   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Severe acute multi-systemic failure with bilateral ocular toxoplasmosis in immunocompetent patients from urban settings in Colombia: Case reports

American Journal of Ophthalmology Case Reports, 2020
Propose: To report two cases of severe acute multi-systemic failure with bilateral ocular toxoplasmosis in immunocompetent patients from urban settings in Colombia.
Diana Alejandra Cortés, María Camila Aguilar, Hernán Andres Ríos, Francisco José Rodríguez, Kelly Verónica Montes, Jorge Enrique Gómez- Marín, Alejandra de-la-Torre   +6 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

The diverse multi-modal imaging findings of recurrent primary vitreoretinal lymphoma

American Journal of Ophthalmology Case Reports, 2020
We present a case of a 44-year-old man with biopsy-proven primary vitreoretinal lymphoma (PVRL), who developed multiple ocular recurrences over the course of six years.
Jennifer Lee, Debra A. Goldstein
doaj   +1 more source

Anti-TNF-Alpha Associated Central Nervous System Demyelination. Drug-Induced Demyelination or Multiple Sclerosis Trigger? A Case Series. [PDF]

Clin Case Rep
ABSTRACT Adalimumab is a monoclonal antibody that targets TNF‐α and is effective in treating several autoimmune disorders, including non‐infectious uveitis; however, it has been associated with demyelinating lesions. This study presents two cases of CNS demyelination in patients who consumed adalimumab. First, an 18‐year‐old man presented with subacute
Abutorabi-Zarchi M, Ziyaei A, Ghane D.
europepmc   +2 more sources

Causes of Red Eye-Uveitis

, 2012
Uveitis, being an important cause of ocular morbidity, must be taken into consideration in the differential diagnosis and the management of patients with red eye. Uveitis entities can demonstrate variable clinical features.
Selçuk Sızmaz
core   +1 more source